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Kishore V. L. Parsa

Researcher at University of Hyderabad

Publications -  73
Citations -  1798

Kishore V. L. Parsa is an academic researcher from University of Hyderabad. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 21, co-authored 62 publications receiving 1600 citations. Previous affiliations of Kishore V. L. Parsa include Texas A&M University–Kingsville & Ohio State University.

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Use of polyethyleneimine polymer in cell culture as attachment factor and lipofection enhancer

TL;DR: Polyethyleneimine is an effective attachment factor for weakly anchoring cell lines and primary cells and increases the yield of expressed products with commonly used cell lines such as PC-12 and HEK-293 cells.
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Pulmonary Surfactant Protein A Regulates TLR Expression and Activity in Human Macrophages

TL;DR: A critical role is identified for SP-A in modulating the lung inflammatory response by regulating macrophage TLR activity during the differentiation of primary human monocytes into macrophages.
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Akt/Protein kinase B modulates macrophage inflammatory response to Francisella infection and confers a survival advantage in mice.

TL;DR: It is demonstrated that F. novicida infection of murine macrophages induces the activation of Akt, and that Akt activation may be regulated by bacterial genes associated with phagosomal escape, thereby contributing to immunity against F.novicida.
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A new three-component reaction: green synthesis of novel isoindolo[2,1-a]quinazoline derivatives as potent inhibitors of TNF-α

TL;DR: Concurrent construction of five and six membered fused N-heretocyclic ring was achieved via a conceptually new three-component reaction affording 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-diones as novel inhibitors of TNF-α in vitro.
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Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes.

TL;DR: The present review summarizes the latest preclinical and clinical trial data of different DPP IV inhibitors with a special emphasis on their DPP8/9 fold selectivity and therapeutic advantages over GLP-1 based approach.