Showing papers by "Kodiveri Muthukaliannan Gothandam published in 2023"
TL;DR: Li et al. as mentioned in this paper conducted a systematic review and meta-analysis on the prevalence of human papillomavirus (HPV) DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia.
Abstract: It is with great interest that we read the results of Zhuang Li and colleagues’ systematic review and meta-analysis. 1 Li Z Liu P Wang Z et al. Prevalence of human papillomavirus DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia: a systematic review and meta-analysis. Lancet Oncol. 2023; 24: 403-414 Summary Full Text Full Text PDF PubMed Scopus (0) Google Scholar We laud the authors on their stratification of data on the basis of geography, including regions that have traditionally had a low prevalence of human papillomavirus (HPV) implicated in vulvar carcinomas (ie, vulvar cancer and vulvar intraepithelial neoplasia). We would like to offer our constructive critique of their analysis. Prevalence of human papillomavirus DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia: a systematic review and meta-analysisThe high prevalence of HPV16 and HPV33 in vulvar cancer and vulvar intraepithelial neoplasia emphasised the importance of nine-valent HPV vaccination in preventing vulvar neoplasm. Additionally, this study highlighted the potential clinical significance of double positivity for HPV DNA and p16INK4a in vulvar neoplasm. Full-Text PDF HPV DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasiaWe are writing to express our concerns regarding Zhuang Li and colleagues’ systematic review and meta-analysis.1 Although the study provides valuable insights, we have identified several issues that require addressing. Full-Text PDF HPV DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia – Authors' replyWe thank Abhishek Anil and colleagues and Rama Jayaraj and colleagues for their interest and comments on our Article1 concerning the prevalence of human papillomavirus (HPV) DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia. Full-Text PDF