scispace - formally typeset
K

Kwang-Hyeon Liu

Researcher at Kyungpook National University

Publications -  215
Citations -  5404

Kwang-Hyeon Liu is an academic researcher from Kyungpook National University. The author has contributed to research in topics: Microsome & Metabolite. The author has an hindex of 34, co-authored 208 publications receiving 4575 citations. Previous affiliations of Kwang-Hyeon Liu include Seoul National University & Dankook University.

Papers
More filters
Journal ArticleDOI

LipidBlast in silico tandem mass spectrometry database for lipid identification

Tobias Kind, +7 more
- 01 Aug 2013 - 
TL;DR: This work provides a freely available computer-generated tandem mass spectral library of 212,516 spectra covering 119,200 compounds from 26 lipid compound classes, including phospholipids, glycerolipid, bacterial lipoglycans and plant glycolipids.
Journal ArticleDOI

Adjunctive Treatment With a Dopamine Partial Agonist, Aripiprazole, for Antipsychotic-Induced Hyperprolactinemia: A Placebo-Controlled Trial

Joo Cheol Shim, +7 more
- 01 Sep 2007 - 
TL;DR: Adjunctive aripiprazole treatment reversed hyperprolactinemia in both sexes, resulting in reinstatement of menstruation in female patients, with no significant effects on psychopathology and extrapyramidal symptoms.
Journal ArticleDOI

High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.

Min-Jung Kim, +6 more
- 30 Sep 2005 - 
TL;DR: A HTS method for potential interactions of inhibitory drugs for nine human P450 enzymes using cocktail incubation and tandem mass spectrometry in vitro and validated by comparing the inhibition data obtained from the incubation of each individual probe substrate alone with data from the new method.
Journal ArticleDOI

Development of the “Inje Cocktail” for High‐throughput Evaluation of Five Human Cytochrome P450 Isoforms in vivo

J Y Ryu, +6 more
- 01 Nov 2007 - 
TL;DR: The new five‐drug cocktail regimen, named the “Inje cocktail,” can be used as a tool to phenotype in vivo enzyme activities of CYP1A2, CYP2C9, CYp2C19, CyP2D6, and CYP3A with only 4 h blood sampling and 8’h urine collection following simultaneous administration of the five probe drugs.
Journal ArticleDOI

Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states.

Kyung Sang Yu, +11 more
- 01 Aug 2004 - 
TL;DR: The objective was to investigate the effect of the CYP3A5 genotype on the systemic clearance of midazolam in constitutive, inhibited, and induced metabolic conditions.