L
L. F. Jerva
Researcher at Pennsylvania State University
Publications - 1
Citations - 489
L. F. Jerva is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Binding site & Reverse transcriptase. The author has an hindex of 1, co-authored 1 publications receiving 476 citations.
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Mechanism and fidelity of HIV reverse transcriptase.
TL;DR: Analysis of the kinetics of processive synthesis suggested that the initial binding of dNTP leads to a faster rate of dissociation of DNA from the enzyme, and further investigation supported a two-step dN TP binding mechanism with the formation of an initial E.DNA.dNTP complex.