L
L. Gandini
Researcher at University of Bologna
Publications - 33
Citations - 1355
L. Gandini is an academic researcher from University of Bologna. The author has contributed to research in topics: Sperm & Male infertility. The author has an hindex of 14, co-authored 33 publications receiving 1287 citations. Previous affiliations of L. Gandini include Sapienza University of Rome.
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Lipids of the sperm plasma membrane: from polyunsaturated fatty acids considered as markers of sperm function to possible scavenger therapy
TL;DR: A specific composition of phospholipids and a significant concentration of polyunsaturated fatty acids (PUFA) have been shown to be present in sperm membranes and Seminal plasma has a highly specialized scavenger system that defends the sperm membrane against lipoperoxidation.
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Placebo-controlled, double-blind, cross-over trial of glutathione therapy in male infertility.
TL;DR: It is indicated that glutathione therapy could represent a possible therapeutical tool for both of the selected andrological pathologies and demonstrate a statistically significant positive effect on sperm motility.
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Fatty acid composition of spermatozoa and immature germ cells.
TL;DR: This study demonstrates that the human germ cell line can elongate and desaturate essential fatty acids and that the percentage of long-chain PUFA is correlated with the normal morphology of sperm cells.
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Lipoperoxidation damage of spermatozoa polyunsaturated fatty acids (PUFA): scavenger mechanisms and possible scavenger therapies.
TL;DR: The lipid metabolism in sperm cells is important both as one of the main sources for energy production and for cell structure and the double leaflets of the membrane should be considered not simply as a passive lipid film, but as a very specialized structure.
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Nuclear chromatin variations in human spermatozoa undergoing swim-up and cryopreservation evaluated by the flow cytometric sperm chromatin structure assay.
TL;DR: The results showed that post-rise spermatozoa represent a subpopulation characterized by a general improvement of the morphological (reduction of the percentage of abnormal forms and heads, increase of the green head sperm percentage) and kinetic parameters, indicative of optimal fertilizing ability.