L
L. Henry Edmunds
Researcher at University of Pennsylvania
Publications - 96
Citations - 7013
L. Henry Edmunds is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Cardiopulmonary bypass & Mitral valve. The author has an hindex of 41, co-authored 96 publications receiving 6863 citations. Previous affiliations of L. Henry Edmunds include Medical University of South Carolina & Harvard University.
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Journal ArticleDOI
ACC/AHA Guidelines for the Management of Patients With Valvular Heart Disease A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Valvular Heart Disease)
RobertO. Bonow,Blase A. Carabello,AntonioC. de Leon,L. Henry Edmunds,BradleyJ. Fedderly,MichaelD. Freed,WilliamH. Gaasch,CharlesR. McKay,RickA. Nishimura,PatrickT. O’Gara,RobertA. O’Rourke,ShahbudinH. Rahimtoola,JamesL. Ritchie,MelvinD. Cheitlin,KimA. Eagle,TimothyJ. Gardner,Arthur Garson,R. J. Gibbons,RichardO. Russell,ThomasJ. Ryan,SidneyC. Smith +20 more
TL;DR: It is important that the medical profession play a significant role in critically evaluating the use of diagnostic procedures and therapies in the management or prevention of disease states.
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Effect of Annular Shape on Leaflet Curvature in Reducing Mitral Leaflet Stress
Ivan S. Salgo,Joseph H. Gorman,Robert C. Gorman,Benjamin M. Jackson,Frank W. Bowen,Theodore Plappert,Martin St. John Sutton,L. Henry Edmunds +7 more
TL;DR: The saddle shape of the mitral annulus confers a mechanical advantage to the leaflets by adding curvature, which may be valuable when leaflet curvature becomes reduced due to diminished leaflet billowing caused by annular dilatation.
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Inflammatory response to cardiopulmonary bypass
TL;DR: The roles of the contact and complement systems and of neutrophils and monocytes in the inflammatory response to cardiopulmonary bypass and open heart operation are reviewed.
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Release of vasoactive substances during cardiopulmonary bypass.
TL;DR: This essay briefly reviews the actions, sources, and perturbations of the approximately 25 vasoactive substances known or believed to be altered by cardiopulmonary bypass, and provides an introductory reference list.
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Thrombotic and bleeding complications of prosthetic heart valves.
TL;DR: The adequacy of warfarin anticoagulation is the most important factor affecting thrombotic and bleeding complications in patients with mechanical valves and over shadows the dubious importance of other phenomena such as atrial fibrillation and left atrial thrombus.