L
L. Metwally
Researcher at Suez Canal University
Publications - 29
Citations - 561
L. Metwally is an academic researcher from Suez Canal University. The author has contributed to research in topics: Antibiotic resistance & Viral hepatitis. The author has an hindex of 13, co-authored 26 publications receiving 506 citations. Previous affiliations of L. Metwally include Belfast Health and Social Care Trust.
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Journal ArticleDOI
A prospective clinical trial of a real-time polymerase chain reaction assay for the diagnosis of candidemia in nonneutropenic, critically ill adults.
Ronan McMullan,L. Metwally,Peter V. Coyle,S. Hedderwick,Brian McCloskey,H.J. O'Neill,Christopher Patterson,G. Thompson,C. H. Webb,Roderick J. Hay +9 more
TL;DR: Three TaqMan-based real-time polymerase chain reaction assays were developed that are capable of detecting the main medically important Candida species, categorized according to the likelihood of fluconazole susceptibility and performed well in a prospective trial of nonneutropenic adults in a single intensive care unit.
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Timing of urinary catheter removal after uncomplicated total abdominal hysterectomy: a prospective randomized trial
TL;DR: Removal of the urinary catheter 6h postoperatively appears to be more advantageous than early or late removal in cases of uncomplicated total abdominal hysterectomy.
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Improving molecular detection of Candida DNA in whole blood: comparison of seven fungal DNA extraction protocols using real-time PCR
L. Metwally,Derek Fairley,Peter Coyle,Roderick J. Hay,S. Hedderwick,Brian McCloskey,H.J. O'Neill,C. H. Webb,W Elbaz,Ronan McMullan +9 more
TL;DR: The YeaStar method enabled C. albicans DNA to be detected with highest sensitivity over the entire range of copy numbers evaluated, and appears to be an optimal method for extracting Candida DNA from whole blood.
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High prevalence of Klebsiella pneumoniae carbapenemase-mediated resistance in K. pneumoniae isolates from Egypt.
TL;DR: Real-time PCR assay was used in a tertiary care hospital in Egypt to test ertapenem-nonsusceptible isolates of K. pneumoniae for the presence of the blaKPC gene and compared the results with modified Hodge test to report high prevalence of ertAPenem nonsusceptibility.
Journal ArticleDOI
Rapid differentiation between fluconazole-sensitive and -resistant species of Candida directly from positive blood-culture bottles by real-time PCR
L. Metwally,G. Hogg,Peter Coyle,R. J. Hay,S. Hedderwick,Brian McCloskey,H.J. O'Neill,G.M. Ong,G. Thompson,C. H. Webb,Ronan McMullan +10 more
TL;DR: The reported assay significantly reduces the time required to identify the presence of C. glabrata and C. krusei in comparison with a conventional phenotypic method, from approximately 72 to <3 h, and consequently allows optimization of the antifungal regimen at an earlier stage.