Showing papers by "L. Stefan Lohmander published in 1994"

Knee ligament injury, surgery and osteoarthrosis: Truth or consequences?

Abstract: We reviewed reports that describe development of osteoarthrosis of the knee after anterior cruciate ligament or meniscus injury. The occurrence of posttraumatic osteoarthrosis varied considerably from one report to another. The literature does not lend support to the efficacy of cruciate ligament repair or reconstruction in retarding the progression of osteoarthrosis after knee injury. We encourage prospective, controlled, randomized and masked studies that aim to evaluate the utility of ligament reconstruction, meniscus suture or meniscus transplantation for preventing posttraumatic osteoarthrosis.

Intraarticular injections of hyaluronan in patients with cartilage abnormalities and knee pain : a one-year double-blind, placebo-controlled study

Abstract: Objective. To compare the effect of intraarticular injections of hyaluronan and placebo (vehicle, saline) in patients with knee pain on exertion and with joint cartilage abnormalities. Methods. Fifty-two patients with arthroscopically verified deep cartilage fissures and villus-like flakes in the symptomatic knee were randomly assigned to receive intraarticular injections of 2.5 ml of either hyaluronan or vehicle, weekly for 5 weeks. The effect was evaluated by both primary and secondary parameters of efficacy at 2, 4, 13, 26, and 52 weeks. Results. At the followup visits, both groups had improvement from baseline; however, there was no difference between the groups in any of the relevant variables at any time point. Conclusion. The effects of intraarticular hyaluronan do not differ significantly from those of placebo in patients with knee pain and cartilage disease. (Less)