Compounds of formulae I and II are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and manage serotonin-mediated diseases and disorders.

Multicyclic amino acid derivatives and methods of their use

This invention is directed to a reactive distillation process and system for the alkylation of liquid aromatic compounds with a liquid olefin or olefin/paraffin mixture. The aromatic compound may have from about 6 to about 30 carbons and the olefin may have from about 8 to 30 carbons. The system has a reactor configuration utilizing an alkylation catalyst, a reboiler with product takeoff, and a feed inlet above the catalyst bed. The system may also include a means for in-situ mixing of the aromatic compound and olefin or olefin/paraffin mixture, an overhead condenser and/or a water takeoff.

Process and system for alkylation of aromatic compounds

This invention is directed to a fluorine-containing mordenite catalyst and use thereof in the manufacture of linear alkylbenzene (LAB) by alkylation of benzene with an olefin. The olefin may have from about 10 to 14 carbons. The fluorine-containing mordenite is prepared typically by treatment with an aqueous hydrogen fluoride solution. The benzene alkylation may be conducted using reactive distillation.

Alkylation of benzene to form linear alkylbenzenes using fluorine-containing mordenites

In a two step alkylation process for the preparation of monoalkylated benzene, benzene and an olefin with 5 to 30 carbon atoms are contacted first in presence of a fluorine-containing mordenite and then in presence of a fluorine-containing clay.

Two-step process for alkylation of benzene to form linear alkylbenzenes

The present invention is directed to a zeolite Y catalyst having a controlled macropore structure. The present invention is also directed to a zeolite Y catalyst composite and a process for preparing the catalyst composite. The catalyst composite exhibits reduced deactivation rates during the alkylation process, thereby increasing the life of the catalyst. The present invention is also directed to processes for the preparation of carbonated, overbased aromatic sulfonates, which processes comprise alkylation, carbonation of aromatic hydrocarbons with one or more olefins.

Zeolite Y alkylation catalysts

A catalytic process for the selective alkylation of mono- and polycyclic aromatic hydrocarbons is described. The aromatic hydrocarbon is reacted with an alkylating agent in the presence of an acid form of a dealuminated small pore mordenite catalyst having an atomic ratio Si/Al of at least 10:1 to thereby yield the desired alkyl substituted derivative with improved selectivity and improved yield.

Lardinois Pierre Fernand Marce

Papers

Catalytic process for selective alkylation of aromatic hydrocarbons

Improved catalytic process for selective alkylation of aromatic hydrocarbons