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Showing papers by "Larry Reitzer published in 2009"

Journal Article•DOI•
Rrp2, a σ 54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner

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Jon S. Blevins1, Jon S. Blevins2, Hai-Jun Xu3, Ming He3, Michael V. Norgard1, Larry Reitzer4, X. Frank Yang3 •
University of Texas Southwestern Medical Center1, University of Arkansas for Medical Sciences2, Indiana University3, University of Texas at Dallas4
15 Apr 2009-Journal of Bacteriology
TL;DR: It is shown that recombinant Rrp2 binds to DNA in a sequence-nonspecific manner and activates sigma(54)-dependent rpoS expression without an apparent upstream enhancer element commonly associated with other s Sigma( 54)-dependent transcriptional activators.
Abstract: Rrp2 is the sole σ54-dependent transcriptional activator present in the Borrelia burgdorferi genome. We showed that recombinant Rrp2 binds to DNA in a sequence-nonspecific manner. During infection, Rrp2 activates σ54-dependent rpoS expression without an apparent upstream enhancer element commonly associated with other σ54-dependent transcriptional activators.

58 citations