L
Laura A. DeNardo
Researcher at University of California, Los Angeles
Publications - 25
Citations - 1146
Laura A. DeNardo is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Prefrontal cortex & Medicine. The author has an hindex of 9, co-authored 17 publications receiving 704 citations. Previous affiliations of Laura A. DeNardo include Howard Hughes Medical Institute & University of California, San Diego.
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Journal ArticleDOI
Temporal evolution of cortical ensembles promoting remote memory retrieval
Laura A. DeNardo,Cindy D. Liu,Cindy D. Liu,William E. Allen,William E. Allen,Eliza L. Adams,Drew Friedmann,Drew Friedmann,Lisa Fu,Lisa Fu,Casey J. Guenthner,Casey J. Guenthner,Marc Tessier-Lavigne,Liqun Luo,Liqun Luo +14 more
TL;DR: TRAP2, which allows genetic access to neurons based on their activity, is characterized and used to show that neuronal ensembles in prelimbic cortex for remote fear memory undergo dynamic changes during the first 14 days after learning.
Journal ArticleDOI
Thirst-associated preoptic neurons encode an aversive motivational drive
William E. Allen,Laura A. DeNardo,Michael Z. Chen,Cindy D. Liu,Cindy D. Liu,Kyle M. Loh,Lief E. Fenno,Charu Ramakrishnan,Karl Deisseroth,Karl Deisseroth,Liqun Luo,Liqun Luo +11 more
TL;DR: The activity of dehydration-activated MnPO neurons establishes a scalable, persistent, and aversive internal state that dynamically controls thirst-motivated behavior.
Journal ArticleDOI
Connectivity of mouse somatosensory and prefrontal cortex examined with trans-synaptic tracing
TL;DR: This work used rabies virus–based trans-synaptic tracing to analyze the laminar distribution of local and long-range inputs to pyramidal neurons in the mouse barrel cortex and medial prefrontal cortex and found layer-specific input patterns were largely independent of NMDA receptor function in the recipient neurons.
Journal ArticleDOI
Genetic strategies to access activated neurons.
Laura A. DeNardo,Liqun Luo +1 more
TL;DR: Genetic strategies to access activated neurons and characterize their functional properties, molecular profiles, connectivity, and causal roles in sensory-coding, memory, and valence-encoding are reviewed.
Journal ArticleDOI
Teneurin-3 controls topographic circuit assembly in the hippocampus.
Dominic S. Berns,Laura A. DeNardo,Laura A. DeNardo,Daniel T. Pederick,Daniel T. Pederick,Liqun Luo,Liqun Luo +6 more
TL;DR: It is shown that mouse teneurin-3 is expressed in multiple topographically interconnected areas of the hippocampal region, including proximal CA1, distal subiculum, and medial entorhinal cortex, and it is suggested that the assembly of a complex distributed circuit in the mammalian brain may be orchestrated via matching expression and homophilic attraction.