L
Laura M. Holsen
Researcher at Brigham and Women's Hospital
Publications - 65
Citations - 2697
Laura M. Holsen is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Medicine & Orbitofrontal cortex. The author has an hindex of 27, co-authored 52 publications receiving 2251 citations. Previous affiliations of Laura M. Holsen include Harvard University & University of Wisconsin-Madison.
Papers
More filters
Journal ArticleDOI
Neural mechanisms associated with food motivation in obese and healthy weight adults.
Laura E. Martin,Laura M. Holsen,Rebecca J. Chambers,Amanda S. Bruce,William Brooks,Jennifer R. Zarcone,Merlin G. Butler,Cary R. Savage +7 more
TL;DR: Functional magnetic resonance imaging results indicate that brain function associated with food motivation differs in obese and HW adults and may have implications for understanding brain mechanisms contributing to overeating and obesity, and variability in response to diet interventions.
Journal ArticleDOI
Obese children show hyperactivation to food pictures in brain networks linked to motivation, reward and cognitive control
Amanda S. Bruce,Laura M. Holsen,Rebecca J. Chambers,Laura E. Martin,William Brooks,Jennifer R. Zarcone,Merlin G. Butler,Cary R. Savage +7 more
TL;DR: Initial evidence is provided that obesity, even among children, is associated with abnormalities in neural networks involved in food motivation, and that the origins of neural circuitry dysfunction associated with obesity may begin early in life.
Journal ArticleDOI
Neural mechanisms underlying food motivation in children and adolescents.
Laura M. Holsen,Jennifer R. Zarcone,Travis Thompson,William Brooks,Mary F. Anderson,Jasjit S. Ahluwalia,Nicole L. Nollen,Cary R. Savage +7 more
TL;DR: Findings provide evidence that normal patterns of neural activity related to food motivation begin in childhood, and have implications for obese children and adults, who may have abnormal hunger and satiation mechanisms.
Journal ArticleDOI
Neural mechanisms underlying hyperphagia in Prader-Willi syndrome.
Laura M. Holsen,Jennifer R. Zarcone,William Brooks,Merlin G. Butler,Travis Thompson,Jasjit S. Ahluwalia,Nicole L. Nollen,Cary R. Savage +7 more
TL;DR: Functional magnetic resonance imaging was used to study the neural mechanisms underlying responses to visual food stimuli, before and after eating, in individuals with PWS and a healthy weight control (HWC) group.
Journal ArticleDOI
Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa
Laura M. Holsen,Elizabeth A. Lawson,Justine I. Blum,Eunice Ko,Nikos Makris,Pouneh K. Fazeli,Anne Klibanski,Jill M. Goldstein +7 more
TL;DR: The data provide evidence of potential state and trait hypoactivations in food motivation regions involved in the assessment of food's reward value and integration of these with interoceptive signalling of one's internal state of well-being, with important relations between brain activity and homeostatic and hedonic aspects of appetite.