Rook's textbook of dermatology , Rook's textbook of dermatology , کتابخانه مرکزی دانشگاه علوم پزشکی ایران

Rook's Textbook of Dermatology

Atopic dermatitis is a common and chronic, pruritic inflammatory skin condition that can affect all age groups. This evidence-based guideline addresses important clinical questions that arise in its management. In this second of 4 sections, treatment of atopic dermatitis with nonpharmacologic interventions and pharmacologic topical therapies are reviewed. Where possible, suggestions on dosing and monitoring are given based on available evidence.

https://www.jaad.org/article/S0190-9622(14)01257-2/pdf

Guidelines of care for the management of atopic dermatitis: Section 2. Management and treatment of atopic dermatitis with topical therapies

Atopic dermatitis (AD) is a chronic, pruritic, inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important clinical questions that arise in the management and care of AD, providing updated and expanded recommendations based on the available evidence. In this first of 4 sections, methods for the diagnosis and monitoring of disease, outcomes measures for assessment, and common clinical associations that affect patients with AD are discussed. Known risk factors for the development of disease are also reviewed.

http://blackbook.com.br/wp-content/uploads/2014/02/OK-aad-2012-atopic-dermatitis-guideline-part-1-article-in-press.pdf

Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis.

Icmje

Diseases of the Skin

Give us 5 minutes and we will show you the best book to read today. This is it, the andrews diseases of the skin clinical dermatology that will be your best choice for better reading book. Your five times will not spend wasted by reading this website. You can take the book as a source to make better concept. Referring the books that can be situated with your needs is sometime difficult. But here, this is so easy. You can find the best thing of book that you can read.

Andrews’ Diseases of the Skin: Clinical Dermatology

https://www.cidjournal.com/article/S0738-081X(04)00041-0/pdf

The assessment of acne: An evaluation of grading and lesion counting in the measurement of acne

Objectives The authors assessed the efficacy of a ceramide-dominant, triple-lipid barrier repair formulation (EpiCeram), which designed to correct the lipid-biochemical abnormalities in atopic dermatitis (AD) in comparison to fluticasone propionate cream. Methods In a five-center, investigator-blinded, randomized trial, EpiCeram was compared to fluticasone (Cutivate) cream in 121 patients with moderate-to-severe AD. Primary outcome measures were: 1) reduction in disease severity, assessed as SCORAD (Severity Scoring for Atopic Dermatitis) scores; 2) improvement in pruritus; and 3) improvements in sleep habits. Results EpiCeram reduced clinical disease severity, decreased pruritus and improved sleep habits both 14 and 28 days after initiation of therapy. Although the fluticasone-treated group showed significantly greater improvement at 14 days, SCORAD, pruritus and sleep habit scores for EpiCeram did not differ significantly from the fluticasone-treated group by 28 days. Conclusion The ceramide-dominant, physiological-lipid based formulation could represent an effective stand-alone or ancillary therapy for many pediatric patients with AD.

Efficacy of a lipid-based barrier repair formulation in moderate-to-severe pediatric atopic dermatitis.

Cockroaches have great significance for the dermatologic finger nails, and other hard parts of the soles of the feet and palms of the hands, nibbled by [the roaches].’’3 Other community, if only because of the many reports and claims implicating the cockroach as a vector for human disease. reports, dating back to the early 1700s and continuing through the 1900s, confirm that roaches will bite humans,4 This review discusses aspects fundamental to cockroach biology and summarizes some of the basic and clinical although there do not appear to be any reports of someone actually dying from these attacks. One writer described the scientific works which contribute to the claims about roaches. roach as ‘‘a destructive insect to clothes, books, c nevertheless, there is a growing population of at least 3500 Roach oddities named species, which range in length from 5 mm to 90 mm.1 Although one is apt to think of roaches primarily as The current view of the roach appears to have come full circle from being an object of man’s longing to an object pests, far less than 1% of roach species actually cause concern for humans;1 however, some of the early records of most people’s loathing. Roaches have been used in one manner or another to treat about 30 medical conditions of human interaction with cockroaches might lead one to think otherwise. Consider these letters to Nature in 1870, of humans, ranging from boils and indigestion to warts and heart disease.4 Specifically, in the mid-1800s, a powder ‘‘A [sailor] was marked for life by [roaches] on board a ship coming home from Jamaica.’’2 The writer goes on to made from dried cockroaches was recommended as a diuretic;6 however, the efficacy of these concoctions has say, ‘‘I have known bread, &c., in the West Indies uneatable from being run over by the small dark Cockroach...while never been substantiated. While roaches are known to be found in kitchens, in the great pale species...is utterly unbearable.’’2 One might think these were great beasts with which to contend, given cabinets, or on counters, even in the most clean homes, they have also been found in other places. Specifically, the following account, ‘‘In some ships infested with these insects, sailors frequently complain of having their toe and roaches have been reported to crawl into the most incon90

The medical importance of cockroaches

Background New antibacterial agents with activity against pathogenic strains resistant to established antibiotics are needed to treat patients with secondarily infected dermatitis (SID). Objective We sought to determine the clinical safety and efficacy of topical retapamulin ointment 1% versus oral cephalexin for the treatment of SID. Methods Patients with SID were randomly assigned to retapamulin ointment 1% (twice daily [bid]) for 5 days, or oral cephalexin (500 mg bid) for 10 days. The primary efficacy end point was clinical response at follow-up. Secondary outcomes included microbiologic response at follow-up, safety, and compliance. Results Retapamulin was as effective as cephalexin (clinical success rates at follow-up: 85.9% and 89.7%, respectively). Microbiologic success rates at follow-up were 87.2% for retapamulin and 91.8% for cephalexin. Retapamulin was well tolerated and the topical formulation was preferred over the oral drug. Limitations An imbalance existed in the number of patients with the clinical outcome "unable to determine" (15 retapamulin, 2 cephalexin), mainly because of their failure to attend the study visit. If those who failed to attend visits (who did not withdraw as a result of drug-related events) are removed from the analysis, the clinical success rates are 89.9% for retapamulin and 89.7% for cephalexin. Conclusions Retapamulin ointment 1% (bid) for 5 days was as effective as oral cephalexin (bid) for 10 days in treatment of patients with SID, and was well tolerated.

Topical retapamulin ointment (1%, wt/wt) twice daily for 5 days versus oral cephalexin twice daily for 10 days in the treatment of secondarily infected dermatitis: results of a randomized controlled trial.

Lawrence Charles Parish

Papers

Andrews’ Diseases of the Skin: Clinical Dermatology

The assessment of acne: An evaluation of grading and lesion counting in the measurement of acne

Efficacy of a lipid-based barrier repair formulation in moderate-to-severe pediatric atopic dermatitis.

The medical importance of cockroaches

Topical retapamulin ointment (1%, wt/wt) twice daily for 5 days versus oral cephalexin twice daily for 10 days in the treatment of secondarily infected dermatitis: results of a randomized controlled trial.