Showing papers by "Lee Goldman published in 2010"
TL;DR: Aging and population growth will increase cardiovascular disease by more than a half over the coming 20 years, and projected unfavorable trends in blood pressure, total cholesterol, diabetes, and body mass index may accelerate the epidemic.
Abstract: Background— The relative effects of individual and combined risk factor trends on future cardiovascular disease in China have not been quantified in detail.
Methods and Results— Future risk factor trends in China were projected based on prior trends. Cardiovascular disease (coronary heart disease and stroke) in adults ages 35 to 84 years was projected from 2010 to 2030 using the Coronary Heart Disease Policy Model–China, a Markov computer simulation model. With risk factor levels held constant, projected annual cardiovascular events increased by >50% between 2010 and 2030 based on population aging and growth alone. Projected trends in blood pressure, total cholesterol, diabetes (increases), and active smoking (decline) would increase annual cardiovascular disease events by an additional 23%, an increase of approximately 21.3 million cardiovascular events and 7.7 million cardiovascular deaths over 2010 to 2030. Aggressively reducing active smoking in Chinese men to 20% prevalence in 2020 and 10% prevalence in 2030 or reducing mean systolic blood pressure by 3.8 mm Hg in men and women would counteract adverse trends in other risk factors by preventing cardiovascular events and 2.9 to 5.7 million total deaths over 2 decades.
Conclusions— Aging and population growth will increase cardiovascular disease by more than a half over the coming 20 years, and projected unfavorable trends in blood pressure, total cholesterol, diabetes, and body mass index may accelerate the epidemic. National policy aimed at controlling blood pressure, smoking, and other risk factors would counteract the expected future cardiovascular disease epidemic in China.
Received September 21, 2009; accepted March 15, 2010.
355 citations
TL;DR: This interactive feature allows readers to make a decision on the basis of a vignette that is followed by specific options, none of which can be considered either correct or incorrect.
Abstract: This interactive feature allows readers to make a decision on the basis of a vignette that is followed by specific options, none of which can be considered either correct or incorrect. In short essays, experts in thefield then arguefor each of the options. In the online version of this feature, available at NEJM.org, readers can participate in forming community opinion by choosing one of the options and, if they like, providing their reasons.
76 citations
TL;DR: The efficacy and safety of fondaparinux for the treatment of superficial-vein thrombosis in the legs and the results of their carefully conduct study are reported.
Abstract: In this issue of the Journal, Decousus et al.1 report on the efficacy and safety of fondaparinux for the treatment of superficial-vein thrombosis in the legs. The results of their carefully conduct...
20 citations
TL;DR: In this issue, Ford and associates summarize data from several studies that examined the ability of the RCRI to predict major cardiac complications after noncardiac surgery.
Abstract: In this issue, Ford and associates summarize data from several studies that examined the ability of the RCRI to predict major cardiac complications after noncardiac surgery. The editorialist believ...
18 citations