L
Leif Sestoft
Researcher at Gentofte Hospital
Publications - 10
Citations - 292
Leif Sestoft is an academic researcher from Gentofte Hospital. The author has contributed to research in topics: Hypoglycemia & Insulin. The author has an hindex of 8, co-authored 10 publications receiving 291 citations.
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Journal ArticleDOI
Hormonal, Metabolic, and Cardiovascular Responses to Hypoglycemia in Diabetic Autonomic Neuropathy
Jannik Hilsted,Sten Madsbad,Thure Krarup,Leif Sestoft,Niels Johan Christensen,B. Tronier,Henrik Galbo +6 more
TL;DR: During insulin-induced hypoglycemia, patients with autonomic neuropathy had impaired activation of the adrenal medulla, probably due to sympathetic neuropathy, and serum glucose recovery was unaffected and lipolytic responses and blood pressure increments were exaggerated, suggesting increased sensitivity of hepatic glycogenolysis, adipose tissue lipolysis and the cardiovascular system toward the action of catecholamines in diabetics with autonomIC neuropathy.
Journal ArticleDOI
Impaired response of pancreatic polypeptide to hypoglycaemia: an early sign of autonomic neuropathy in diabetics.
TL;DR: Investigating the pancreatic polypeptide response to insulin-induced hypoglycaemia in juvenile diabetics suggested that impaired, secretion of PP may serve as an early sign of autonomic neuropathy in diabetes.
Journal ArticleDOI
No Response of Pancreatic Hormones to Hypoglycemia in Diabetic Autonomic Neuropathy
Jannik Hilsted,Sten Madsbad,Thure Krarup,B. Tronier,Henrik Galbo,Leif Sestoft,Thue W. Schwartz +6 more
TL;DR: The results suggest that autonomic nervous activity is of major importance for pancreatic hormone release during hypoglycemia in man.
Journal ArticleDOI
Hypoglycemia and Hemostatic Parameters in Juvenile-onset Diabetes
TL;DR: Insulin-induced hypoglycemia markedly affects hemostatic balance and may potentially lead to intra-vascular coagulation in juvenile-onset diabetic patients.
Journal ArticleDOI
The importance of plasma free insulin and counterregulatory hormones for the recovery of blood glucose following hypoglycaemia in type 1 diabetics.
TL;DR: It is suggested that enhanced counterregulatory hormone responses in the group with the slow recovery from hypoglycaemia could not compensate for the hypoglycemia effect of a concomitant higher plasma free insulin concentration.