Showing papers by "Leigh T. Canham published in 2003"
TL;DR: In this article, the authors investigated the release of Si(OH) 4 from porous Si films under physiological conditions with the aim of developing a bioavailable form of Si, which is vital for normal bone and connective tissue homeostasis.
Abstract: Silicon (Si) in the form of orthosilicic acid (Si(OH) 4 ) is vital for normal bone and connective tissue homeostasis. Porous Si films release Si(OH) 4 in aqueous solutions in the physiological pH range. This study investigates the release of Si(OH) 4 from porous Si films under physiological conditions with the aim of developing a bioavailable form of Si. Using a standardised technique, porous Si films released increasing Si with time. Dissolution was significant at pH 7 and above, and at a temperature of 37 °C. Higher porosity generally promoted dissolution, however multiple layer films did not show enhanced solubility over corresponding single layer controls. These properties will be used to optimise Si nanostructures that slowly deliver orthosilicic acid in the digestive tract.
223 citations
TL;DR: The 3rd International Conference on Porous Semiconductors (PSST-2002) as discussed by the authors was held in Tenerife, Spain, 10-15 March 2002, with the focus on the progress in the field of porous semiconductors.
Abstract: The 3rd International Conference “Porous Semiconductors – Science and Technology” (PSST-2002) took place in Puerto de la Cruz, Tenerife, Spain, 10–15 March 2002. The meeting critically analyzed the progress in the field of porous semiconductors during two years that passed since the previous PSST-2000 event, whose proceedings were also published in phys. stat. sol. (a) 182, No. 1 (2000). The empha-sis was kept not only on breakthroughs in understanding the mechanism of growth and physical properties and critical issues in luminescence-related applications, but also new applications of porous semiconductors in natural and life sciences, as well in technology were presented. The conference served to join researchers active in physics and chemistry of semiconductors, optics, electrochemistry, analytical instrumentation, biochemistry and other related fields.
The proceedings will be continued in the next issue of phys. stat. sol. (a) 197, No. 2 (2003).
4 citations
Patent•
31 Mar 2003
TL;DR: A mammary fluid collection device as mentioned in this paper comprises at least one silicon storage means 12 and a contact means which when in use causes and/or allows the or one of the silicon storage meant 12 to contact at least part of a breast of a human subject.
Abstract: A mammary fluid collection device 11 comprises at least one silicon storage means 12 and a contact means which when in use causes and/or allows the or at least one of the silicon storage means 12 to contact at least part of a breast of a human subject. The silicon storage means 12 may comprise porous or partially oxidised silicon and may comprise a plurality of silicon needles or barbs. The device may comprise salicyclic acid. The silicon may be derivatised in such a manner that it binds to tumour markers. Also disclosed is a method of collection of mammary fluid. The device and method are for use in the detection of breast cancer.
3 citations
2 citations