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Leith N. Moxon

Researcher at Griffith University

Publications -  14
Citations -  251

Leith N. Moxon is an academic researcher from Griffith University. The author has contributed to research in topics: Alcohol dehydrogenase & Dehydrogenase. The author has an hindex of 9, co-authored 14 publications receiving 248 citations. Previous affiliations of Leith N. Moxon include University of Queensland.

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Genetic variability of alcohol dehydrogenase among Australian Drosophila species: correlation of ADH biochemical phenotype with ethanol resource utilization.

TL;DR: Alcohol dehydrogenase (ADH) activities, electrophoretic phenotypes, and the extent of ethanol resource utilization are compared for three groups of species distinguishable on ecological criteria: the cosmopolitan species D. melanogaster, a frequent inhabitant of wineries; fruit‐baited species of the typically Australian subgenus Scaptodrosophila; and species not attracted to fermented‐fruit baits being collected by sweeping in temperate rain forests.
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Purification and molecular properties of alcohol dehydrogenase from Drosophila melanogaster: Evidence from NMR and kinetic studies for function as an aldehyde dehydrogenase

TL;DR: The specific activity of ADH-FF was 2–3 times higher thanADH-SS with both ethanol and acetaldehyde as dehydrogenase substrates, and ADH and ALDH activities were inhibited by pyrazole, disulphiram and p -hydroxymercuribenzoate.
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The unequivocal determination of lactic acid using a one-dimensional zero-quantum coherence-transfer technique.

TL;DR: The methyl resonances of both lactate and acetaldehyde were readily observed in a mouse brain homogenate by generat‐ ing zero‐quantum coherence using Gaussian pulses for selective excitation of the respective CH resonances.
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The visibility of the 1H NMR signal of ethanol in the dog brain.

TL;DR: The disparity between blood and brain ethanol concentrations was attributed to underestimation of the ethanol concentration due to overlapping resonances with NAA and to T2 attenuation or possible nondetection of the 1H signal from ethanol bound at the surface of cell membranes and partitioned into the hydrophobic core of membrane lipids.
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Water suppression with B0 field gradient homospoil pulses in high-resolution NMR spectroscopy.

TL;DR: The combination of a frequency nonselective excitation suppression method with selective excitation followed by gradient‐induced dephasing of water transverse magnetization yielded suppression ratios of greater than 10,000:1.