L
Lele Ye
Researcher at Wenzhou Medical College
Publications - 15
Citations - 450
Lele Ye is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 7, co-authored 10 publications receiving 236 citations.
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Journal ArticleDOI
Tumor-Infiltrating Immune Cells Act as a Marker for Prognosis in Colorectal Cancer.
Lele Ye,Teming Zhang,Zhengchun Kang,Gangqiang Guo,Sun Yongji,Kangming Lin,Qunjia Huang,Xinyu Shi,Zhonglin Ni,Ning Ding,Kong-Nan Zhao,Wenjun Chang,Junjie Wang,Feng Lin,Xiangyang Xue +14 more
TL;DR: TIICs were correlated with clinical features and prognosis in patients with CRC and thus can be used as markers for prognostic evaluation effectively, and they were more reliable than traditional indicators for evaluating prog outlook in CRC patients.
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New Insights of Emerging SARS-CoV-2: Epidemiology, Etiology, Clinical Features, Clinical Treatment, and Prevention
Gangqiang Guo,Lele Ye,Kan Pan,Yu Chen,Dong Xing,Kejing Yan,Zhiyuan Chen,Ning Ding,Wenshu Li,Hong Huang,Lifang Zhang,Xiaokun Li,Xiangyang Xue +12 more
TL;DR: This review combines experimental and clinical evidence into a systematic analysis and summary of the current progress of research into SARS-CoV-2, from multiple perspectives, with the aim of gaining a better overall understanding of the disease.
Journal ArticleDOI
Hsa_circ_0000479 as a Novel Diagnostic Biomarker of Systemic Lupus Erythematosus.
Gangqiang Guo,Huijing Wang,Huijing Wang,Lele Ye,Xinyu Shi,Kejing Yan,Kangmin Lin,Qunjia Huang,Baoqing Li,Qiaoai Lin,Lejiang Zhu,Xiangyang Xue,Huidi Zhang +12 more
TL;DR: It is suggested that hsa_circ_0000479 has potential as a novel biomarker for the diagnosis of SLE and regulates SLE progression by modulating metabolic pathways and the Wnt signaling pathway.
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Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus.
Gangqiang Guo,Gangqiang Guo,Huijing Wang,Xinyu Shi,Lele Ye,Kejing Yan,Zhiyuan Chen,Huidi Zhang,Zi-Bing Jin,Xiangyang Xue +9 more
TL;DR: Hypermethylated m5C genes in SLE and in NSUN2-knockdown HeLa cells were significantly involved in immune-related and inflammatory pathways, including immune system, cytokine signaling pathway, and interferon signaling.
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The cytomegalovirus protein US31 induces inflammation through mono-macrophages in systemic lupus erythematosus by promoting NF-κB2 activation
Gangqiang Guo,Sisi Ye,Shangdan Xie,Lele Ye,Cong Lin,Min Yang,Xinyu Shi,Fangyan Wang,Baoqing Li,Ming Li,Chaosheng Chen,Lifang Zhang,Huidi Zhang,Xiangyang Xue +13 more
TL;DR: A previously unknown role of the HCMV protein US31 in inducing NF-κB-mediated mono-macrophage inflammation in the pathogenesis and development of SLE is uncovered and provides a foundation for the continued investigation of novel therapeutic targets for SLE patients.