L
Leroy F. Liu
Researcher at Academia Sinica
Publications - 1
Citations - 98
Leroy F. Liu is an academic researcher from Academia Sinica. The author has contributed to research in topics: Gene & Topoisomerase. The author has an hindex of 1, co-authored 1 publications receiving 97 citations.
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Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2.
Chung-Ching Juan,Jaulang Hwang,Angela A. Liu,Jacqueline Whang-Peng,Turid Knutsen,Kay Huebner,Carlo M. Croce,Hui Zhang,James C. Wang,Leroy F. Liu +9 more
TL;DR: In this paper, the human TOP1 gene encoding DNA topoisomerase I (EC 5.99.1.2) was mapped to the long arm of chromosome 20, in the region q12-13.2, by hybridization of a radioactively labeled TOP1 probe to human metaphase chromosomes and to a panel of rodent-human somatic hybrids retaining overlapping subsets of human chromosomes.