L
Leslie A. Wanek
Researcher at St. John's University
Publications - 39
Citations - 3947
Leslie A. Wanek is an academic researcher from St. John's University. The author has contributed to research in topics: Melanoma & Lymphadenectomy. The author has an hindex of 29, co-authored 39 publications receiving 3826 citations.
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Journal ArticleDOI
Prolongation of survival in metastatic melanoma after active specific immunotherapy with a new polyvalent melanoma vaccine.
Donald L. Morton,Leland J. Foshag,Dave S.B. Hoon,J. A. Nizze,Estela Famatiga,Leslie A. Wanek,C. C. Chang,D G Davtyan,Rishab K. Gupta,Robert Elashoff +9 more
TL;DR: The new polyvalent melanoma cell vaccine increased the median and 5-year survival of stage IIIA melanoma patients with regional soft tissue metastases twofold and stage IV patients threefold compared with previous immunotherapy and other treatments.
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Improved long-term survival after lymphadenectomy of melanoma metastatic to regional nodes. Analysis of prognostic factors in 1134 patients from the John Wayne Cancer Clinic.
TL;DR: A mathematical model was developed and found to approximate closely the observed survival rates in the heterogenous subsets and in the group as a whole, and there was considerable heterogeneity, with 5-year survival varying from 79% to 14%.
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Lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: therapeutic utility and implications of nodal microanatomy and molecular staging for improving the accuracy of detection of nodal micrometastases.
Donald L. Morton,Dave S.B. Hoon,Alistair J. Cochran,Roderick R. Turner,Richard Essner,Hiroya Takeuchi,Leslie A. Wanek,Edwin C. Glass,Leland J. Foshag,Eddy C. Hsueh,Anton J. Bilchik,David Elashoff,Robert Elashoff,Charles M. Balch +13 more
TL;DR: SN assessment based on intranodal compartmentalization of lymphatic flow (carbon dye mapping) should increase the accuracy of IH and, in combination with multimarker qRT assessment, will allow confident identification of most patients for whom surgery alone is curative.
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Surgical Resection for Melanoma Metastatic to the Gastrointestinal Tract
TL;DR: Almost all patients with melanoma and GI tract metastases can have palliation of symptoms by surgical intervention with minimal morbidity and mortality, and the high 5-year survival rate associated with complete surgical resection of GI tracts metastases indicates that surgery should be strongly considered for this subgroup of patients.
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Contemporary surgical treatment of advanced-stage melanoma.
TL;DR: The results demonstrate the benefit of surgical resection for advanced-stage melanoma and patients with limited sites and numbers of metastases should be considered for curative resection regardless of the location of the disease.