L
Leslie J. Schoenfield
Researcher at Cedars-Sinai Medical Center
Publications - 76
Citations - 4305
Leslie J. Schoenfield is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Gallstones & Chenodeoxycholic acid. The author has an hindex of 29, co-authored 76 publications receiving 4241 citations. Previous affiliations of Leslie J. Schoenfield include University of Toronto & University of California, Irvine.
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Journal ArticleDOI
Dissolution of cholesterol gallstones by chenodeoxycholic acid.
TL;DR: Chenodeoxycholic acid may offer medical treatment for cholesterol cholelithiasis in man and the ratio of bile acids and lecithin to cholesterol in bile increased in all patients.
Journal ArticleDOI
Gallstones and Laparoscopic Cholecystectomy
John L. Gollan,Gregory B. Bulkley,Anna Mae Diehl,Janet D. Elashoff,Michael P. Federle,Walter J. Hogan,Keith A. Kelly,David L. Massanari,Don W. Powell,Michael F. Sorrell,Joanne A. P. Wilson,Jeffrey S. T. Barkun,Eric B. Bass,Harvey Bernard,David L. Carr-Locke,Robert J. Fitzgibbons,Gary D. Friedman,Thomas R. Gadacz,Alan F. Hofmann,John G. Hunter,Charles K. McSherry,William C. Meyers,Frank G. Moody,David L. Nahrwold,Douglas O. Olsen,Carlos A. Pellegrini,Jacques Perissat,Joseph B. Petelin,Edward H. Phillips,Henry A. Pitt,Leslie J. Schoenfield,Nathaniel J. Soper,Steven M. Strasberg,L. William Traverso,John V. White,Karl A. Zucker,Sarah C. Kaiser,Elsa A. Bray,Bejamin T. Burton,James E. Everhart,John H. Ferguson,Willis R. Foster,Thomas K. Gadacz,William H. Hall,Frank A. Hamilton,Jay H. Hoofnagle,William Meyers +46 more
TL;DR: Gallstones are the most common and most costly digestive disease, with an annual estimated overall cost of more than $5 billion, and the prevalence is higher in women, in association with multiple pregnancies, obesity, and rapid weight loss, as well as in older patients and in certain ethnic groups.
Journal ArticleDOI
Chenodiol (Chenodeoxycholic Acid) for Dissolution of Gallstones: The National Cooperative Gallstone Study: A Controlled Trial of Efficacy and Safety
TL;DR: Chenodiol, 750 mg/d for up to 2 years, is appropriate therapy for dissolution of gallstones in selected patients who are informed of the risks and benefits.
Journal Article
Chenodiol (Chenodeoxycholic Acid) for Dissolution of Gallstones: The National Cooperative Gallstone Study
Leslie J. Schoenfield,John M. Lachin,Richard A. Baum,Robert L. Habig,Russell F. Hanson,Theodore Hersh,N.C. Hightower,Alan F. Hofmann,Elliot C. Lasser,Jay W. Marks,Hagop S. Mekhjian,Ronald Okun,Robert A. Schaefer,Lawrence Shaw,Roger D. Soloway,Johnson L. Thistle,Fred B. Thomas,Malcolm P. Tyor +17 more
TL;DR: A double-masked study was conducted to determine the efficacy and safety of randomly allocated chenodiol (chenodeoxycholic acid, 750 mg/d or 350 mg/D) or placebo administered for 2 years as mentioned in this paper.
Journal ArticleDOI
Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight.
Paul H. Broomfield,Rakesh Chopra,Richard C. Sheinbaum,George G. Bonorris,Alan Silverman,Leslie J. Schoenfield,Jay W. Marks +6 more
TL;DR: It is concluded that ursodeoxycholic acid prevents lithogenic changes in bile and the formation of gallstones in obese subjects during loss of weight.