L
Li-Juan Gao
Researcher at Chengdu University of Traditional Chinese Medicine
Publications - 3
Citations - 59
Li-Juan Gao is an academic researcher from Chengdu University of Traditional Chinese Medicine. The author has contributed to research in topics: Autophagy & Cathepsin D. The author has an hindex of 1, co-authored 3 publications receiving 17 citations.
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Chlorogenic Acid Alleviates Aβ 25-35 -Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway
TL;DR: CGA treatment restored autophagic flux in the brain and alleviated cognitive impairments in APP/PS1 mice via enhanced activation of the mTOR/TFEB signaling pathway.
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Chlorogenic acid enhances autophagy by upregulating lysosomal function to protect against SH‑SY5Y cell injury induced by H 2 O 2
TL;DR: In this paper, a hydrogen peroxide (H2O2) injury cell model was established using SH-SY5Y cells and the influence of chlorogenic acid on cell viability was evaluated using a Cell Counting Kit-8 assay and cell death was assessed using Hoechst 33342 nuclear staining.
Journal ArticleDOI
Ligustilide alleviates neurotoxicity in SH-SY5Y cells induced by Aβ 25-35 via regulating endoplasmic reticulum stress and autophagy
TL;DR: It is demonstrated that Ligustilide significantly decreased the rate of apoptosis, and improved the viability of cells, and could rescue lysosomal function to promote autophagy flux and inhibit the over‐activation of ERS.