L
Li Lu
Researcher at Uppsala University
Publications - 13
Citations - 354
Li Lu is an academic researcher from Uppsala University. The author has contributed to research in topics: Benserazide & Decarboxylase inhibitor. The author has an hindex of 9, co-authored 13 publications receiving 344 citations.
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Journal Article
In Vitro and In Vivo Primate Evaluation of Carbon-11-Etomidate and Carbon-11-Metomidate as Potential Tracers for PET Imaging of the Adrenal Cortex and Its Tumors
Mats Bergström,Thomas A. Bonasera,Li Lu,Elisabeth Bergström,Carin Backlin,Claes Juhlin,Bengt Långström +6 more
TL;DR: Investigations indicate that 11C-etomidate and 12C-metomidate have the potential to be useful specific agents for the visualization of the normal adrenal cortex and to provide positive identification of adrenal cortical tumors.
Journal ArticleDOI
Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography
Håkan Örlefors,Anders Sundin,Anders Sundin,Li Lu,Kjell Öberg,Bengt Långström,Barbro Eriksson,Mats Bergström +7 more
TL;DR: CD premedication improves 11C-5-HTP PET image quality and facilitates detection of NET lesions, and because of the similarity of metabolic pathways, this method could probably be applied to improve PET imaging using other tracers like 18F-DOPA and 11C -DOPA.
Journal Article
In vitro and animal validation of bromine-76-bromodeoxyuridine as a proliferation marker
Mats Bergström,Li Lu,Karl-Johan Fasth,Feng Wu,Erzsebet Bergström-Pettermann,Vladimir Tolmachev,Elisabeth Hedberg,Aiping Cheng,Bengt Långström +8 more
TL;DR: It is suggested that the radioactivity uptake as seen after the administration of 76Br-bromodeoxyuridine, is constituted by two parts: one relating to incorporation into DNA and one existing as free 76Br or metabolites of 76 Br-BrdU.
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Synthesis, in vivo rhesus monkey biodistribution and in vitro evaluation of a 11C-labelled potent aromatase inhibitor: [N-methyl-11C]vorozole.
Pelle Lidström,Thomas A. Bonasera,Dmitrijus Kirilovas,Bo Lindblom,Li Lu,Elisabeth Bergström,Mats Bergström,Jan-Erik Westlin,Bengt Långström +8 more
TL;DR: In vitro, [N-methyl-11C]vorozole displayed high and specific binding to aromatase-rich human placenta and binding to other tissues was lower and less specific, consistent with published Ki values for vorozole.
Journal ArticleDOI
Distribution of 76Br-labeled antisense oligonucleotides of different length determined ex vivo in rats
Feng Wu,Feng Wu,Ulrika Yngve,Elisabeth Hedberg,Michinari Honda,Li Lu,Barbro Eriksson,Yasuyoshi Watanabe,Yasuyoshi Watanabe,Mats Bergström,Bengt Långström +10 more
TL;DR: The potential to perform kinetic whole body studies of (76)Br-oligonucleotides using PET is indicated, with different distribution depending on the oligonucleotide length.