The invention provides a compound ammonium glycyrrhizinate S lyophilized powder composition for injection and a preparation method of the compound ammonium glycyrrhizinate S lyophilized powder composition and relates to the field of medicine. The preparation method comprises the following concrete steps that weighed ammonium glycyrrhizinate, glycine and aspartic acid are added into 8000ml of water for injection, the stirring is carried out so that the materials are dissolved, and the solution is placed for being cooled to 40 DEG C; cysteine hydrochloride, ornithine, calcium disodium edetate and anhydrous sodium sulfite in prescription quantity are added, and the stirring is carried out so that the materials are dissolved; 10 percent of sodium hydroxide solution is used for regulating the PH value to 6.5; sodium dihydrogen phosphate and disodium hydrogen phosphate in the prescription quantity are added, and the stirring is carried out so that the materials are dissolved; active carbon is added, the stirring is carried out for 30 minutes at 60 DEG C, and the decarburization filtering is carried out; 0.45mum and 0.22mum degerming circulation filtering is carried out for 30 minutes; the constant volume of the water for injection is metered to 10000ml; the sampling detection is carried out; filtered liquid medicine is conveyed to a filling chamber; and the filing is carried out after the content detection, the materials enter a freezing-drying box after the filling quantity is determined, and the freezing-drying treatment is carried out. The composition and the preparation method have the advantages that the liquid processing is convenient, the aseptic operation process is simplified, the preparation stability is improved, the moisture content in products can be removed without heat treatment, and the rehydration (dissolving) performance of the preparation is enhanced.

Compound ammonium glycyrrhizinate S lyophilized powder composition for injection and preparation method of compound ammonium glycyrrhizinate S lyophilized powder composition

The invention discloses a composition containing compound ammonium glycyrrhetate S. The composition is composed of the following components in parts by weight: 60-100g of monoammonium glycyrrhizinate S, 600-1000g of glycine, 40-80g of cysteine hydrochloride, 600-1000g of alanine, 600-1000g of histidine, 60-100g of anhydrous sodium sulfite and 60-100g of edetate disodium. The composition is a sodium chloride injection and prepared into 100-200L in total. Compound ammonium glycyrrhetate S has a good liver-protecting effect, has a certain resistance effect on hepatic fibrosis, but is poor in curative effect; according to the invention, through adding alanine and histidine into the compound ammonium glycyrrhetate S, a new compound ammonium glycyrrhetate S pharmaceutical composition is prepared, and therefore the anti-hepatic fibrosis effect is greatly enhanced and the curative effect is more significant.

Composition containing compound ammonium glycyrrhetate S

The invention relates to a compound ammonium glycyrrhizinate S for injection and a making method thereof. The compound ammonium glycyrrhizinate S for injection provided by the invention comprises thefollowing components by weight: 40 parts of ammonium glycyrrhizinate S; 28-32 parts of cysteine hydrochloride; 350-450 parts of glycine; 8-12 parts of Vitamin B; 35-45 parts of anhydrous sodium sulfite; 3.8-4.2 parts of ethylenediamine tetraacetic acid disodium; 14-20 parts of sodium chloride; and 2000-3000 parts of water for injection. The injection has enhanced therapeutic effect on hepatitis patients.

Compound ammonium glycyrrhizinate S for injection and making method thereof

The present invention relates to a compound glycyrrhizin powder injection preparation and its preparation method It is made up by using monoammonium salt glycyrrhizinate, cysteine L-hydrochloride, glycine, anhydrous sodium sulfite, calcium sodium egtazate sodium hydroxide solution and sterile injection water through a certain preparation process

Li Moyang

Papers

Powderd injecta of compounded glycyrrhizin and preparing method