The invention is applicable to the field of biomedical materials, and provides a method for improving the biological activity of a titanium alloy material, the titanium alloy material and application.The method comprises the following steps: preprocessing a titanium alloy material; and injecting the temperature-sensitive collagen doped with the bone morphogenetic protein 9 into pores of the preprocessed titanium alloy material, wherein the titanium alloy material is a 3D printed porous titanium alloy material. The temperature-sensitive collagen doped with the bone morphogenetic protein 9 is implanted into pores and the surface of the 3D printing porous titanium alloy material, the temperature-sensitive collagen is used as a carrier for providing controlled release of the bone morphogeneticprotein 9, the biological activity of the surface of the titanium alloy material can be enhanced, and the bone ingrowth and osseointegration capacity of the titanium alloy material can be effectivelyimproved.

Li Ronghang

Papers

Method for improving biological activity of titanium alloy material, titanium alloy material and application