Li Xiaotong

TL;DR: In this article, the authors describe a concise and straightforward approach to the total syntheses of (+)-Strictifolione and Cryptofolione in the longest linear sequences of four steps and six steps from 3-phenyl propanal.

TL;DR: In this article, a method for synthesizing natural product salvianolic acid A methyl ester was proposed, which is unique and novel in design; key strategies and steps comprise the step of using an easily-removed t-butyldimethylsilyl protecting group as a protecting group of a phenolic hydroxyl group, so that side reaction is avoided; a hyroxyl chiral center of C-8' position is constructed by using Sharpless asymmetric dihydroxylation reaction and using ethylsilane reduction; an alpha, beta

TL;DR: The approach, which characterised a highly diastereoselective chelation-controlled Mukaiyama aldol reaction of a benzyl-protected aldehyde and a Yamaguchi lactonisation of a δ-hydroxy-trans-α,β-unsaturated carboxylic acid, is an alternative synthetic strategy towards cryptocaryalactones.

TL;DR: In this paper, a new synthesis method of a natural product Salvianolic acid F was presented, which comprises the following steps: carrying out hydroxyl group protection on 4-methycatechol used as a raw material, carrying out a methyl radical reaction, and reacting the obtained methyl reaction product with triphenyl phosphine to obtain a phosphorus onium salt of formula 7.

TL;DR: In this paper, a series of nonconjugated methylene-anthracene Schiff base derivatives (DNCAs) were designed and synthesized, and the PXRD profiles demonstrated a transformation from crystalline to amorphous state upon grinding.