L
Lil Träskman
Researcher at Karolinska Institutet
Publications - 12
Citations - 4217
Lil Träskman is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Poison control & Homovanillic acid. The author has an hindex of 12, co-authored 12 publications receiving 4185 citations.
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Journal ArticleDOI
5-HIAA in the Cerebrospinal Fluid: A Biochemical Suicide Predictor?
TL;DR: Patients in the low 5-HIAA mode (below 15 ng/ml) attempted suicide significantly more often than those in the high mode, and they used more violent means.
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Monoamine metabolites in CSF and suicidal behavior.
TL;DR: A follow-up study revealed a 20% mortality by suicide within a year after lumbar puncture in patients with a CSF-HIAA level below the median, which was lower than normal in suicidal patients who were not diagnosed as depressed at the time of lumbr puncture.
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"Serotonin depression"--a biochemical subgroup within the affective disorders?
TL;DR: There was a significant correlation between the concnetration of 5-HIAA and severity of depression in the lower, but not in the upper, mode, which suggests the existence of a biochemical subgroup of depressive disorder, characterized by a disturbance of serotonin turnover.
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Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial.
TL;DR: Clomipramine, but not nortriptyline, was superior to placebo in interview-based ratings of severity of OCD, and the effect was not clear-cut until after five weeks of treatment.
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Clomipramine Treatment of Obsessive-Compulsive Disorder: II. Biochemical Aspects
TL;DR: The amelioration of obsessive-compulsive symptoms was positively correlated to the reduction of CSF concentrations of 5-HIAA during clomipramine treatment but negatively correlated to plasma concentrations of clomIPramine.