L
Lilly Yuen
Researcher at Royal Melbourne Hospital
Publications - 48
Citations - 1218
Lilly Yuen is an academic researcher from Royal Melbourne Hospital. The author has contributed to research in topics: Hepatitis B virus & Hepatitis B. The author has an hindex of 18, co-authored 44 publications receiving 1126 citations. Previous affiliations of Lilly Yuen include The Chinese University of Hong Kong & University of Melbourne.
Papers
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Journal ArticleDOI
Molecular genesis of drug-resistant and vaccine-escape HBV mutants
Stephen Locarnini,Lilly Yuen +1 more
TL;DR: Prevention of resistance requires the adoption of strategies that not only effectively control HBV replication, but also prevent the emergence of ADAPVEMs.
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The L80I Substitution in the Reverse Transcriptase Domain of the Hepatitis B Virus Polymerase Is Associated with Lamivudine Resistance and Enhanced Viral Replication In Vitro
Nadia Warner,Stephen Locarnini,Michael J. Kuiper,Angeline Bartholomeusz,Anna Ayres,Lilly Yuen,Tim Shaw +6 more
TL;DR: Results suggest that coselection of rtL80V/I and rtM204I/V occurs because the former compensates for the loss of replication efficiency associated with the acquisition of LMV resistance, particularly in the case of rm204I.
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Epidemiological and Virological Characteristics of 2 Subgroups of Hepatitis B Virus Genotype C
Henry Lik-Yuen Chan,Stephen Kwok-Wing Tsui,Chi-Hang Tse,Eddie Y. T. Ng,Thomas Chi Chuen Au,Lilly Yuen,Angeline Bartholomeusz,Kwong-Sak Leung,Kin-Hong Lee,Stephen Locarnini,Joseph J.Y. Sung +10 more
TL;DR: HBV genotypes C can be differentiated into 2 subgroups--namely, genotype Ce and genotype Cs--that have different epidemiological distributions and virological characteristics.
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Origins and Evolution of Hepatitis B Virus and Hepatitis D Virus
TL;DR: The current theories of the origin and evolution of HBV are discussed and a model that includes cross-species transmissions and subsequent recombination events on a genetic backbone of genotype C HBV infection is proposed.
Journal ArticleDOI
Possible origins and evolution of the hepatitis B virus (HBV).
TL;DR: A model for the origin and evolution of HBV that involves multiple cross-species transmissions and subsequent recombination events on a background of genotype C HBV infection is proposed.