L
Lina Kassar-Duchossoy
Researcher at Pasteur Institute
Publications - 2
Citations - 1187
Lina Kassar-Duchossoy is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Myogenic regulatory factors & Cell fate determination. The author has an hindex of 2, co-authored 2 publications receiving 1096 citations. Previous affiliations of Lina Kassar-Duchossoy include Centre national de la recherche scientifique.
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Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice
Lina Kassar-Duchossoy,Barbara Gayraud-Morel,Danielle Gomès,Didier Rocancourt,Margaret Buckingham,Vasily Shinin,Shahragim Tajbakhsh +6 more
TL;DR: It is shown that skeletal muscle is present in the new Myf5:Myod double-null mice only when Mrf4 expression is not compromised, which contradicts the widely held view that myogenic identity is conferred solely by Myf 5 and Myod, and identifies Mrf 4 as a determination gene.
Journal ArticleDOI
Pax3/Pax7 mark a novel population of primitive myogenic cells during development
Lina Kassar-Duchossoy,Ellen Giacone,Barbara Gayraud-Morel,Aurélie Jory,Danielle Gomès,Shahragim Tajbakhsh +5 more
TL;DR: This work identifies a novel population of resident Pax3+/Pax7+, muscle marker-negative cells throughout development and shows that these Pax+ cells give rise to muscle progenitors, and provides a framework for defining myogenic cell states for therapeutic studies.