L
Ling-Ling Hsieh
Researcher at Chang Gung University
Publications - 5
Citations - 214
Ling-Ling Hsieh is an academic researcher from Chang Gung University. The author has contributed to research in topics: Sister chromatid exchange & Vinyl chloride. The author has an hindex of 5, co-authored 5 publications receiving 210 citations.
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Journal ArticleDOI
The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function.
TL;DR: Observations suggest that the two genotypes, CYP2E1 and GST T1, may play important roles in the biotransformation of VCM, the effect of which leads to liver damage.
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Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers
TL;DR: The results suggest that VCM workers with ALDH2 1-2/2-2 genotypes, who also smoke, may have increased risk of DNA damage.
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Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
TL;DR: The presence of safrole-DNA adducts in peripheral blood lymphocytes (PBL) is demonstrated and the CYP2E1 would seem to play an important role in the modulation ofsafrole- DNA adduct formation.
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Naturally occurring chlorophyll derivatives inhibit aflatoxin B1-DNA adduct formation in hepatoma cells.
TL;DR: Observations indicate that the chlorophyll derivatives studied may attenuate AFB1-induced DNA damage in the Hepa-1 cell by direct trapping of AFB1.
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XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl chloride workers.
TL;DR: The results suggest that workers with susceptible metabolic and DNA-repair genotypes, may experience an increased risk of DNA damage elicited by VCM exposure.