L
Lucía Graña-Miraglia
Researcher at National Autonomous University of Mexico
Publications - 16
Citations - 431
Lucía Graña-Miraglia is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Acinetobacter baumannii & Genome. The author has an hindex of 8, co-authored 13 publications receiving 269 citations. Previous affiliations of Lucía Graña-Miraglia include University of Toronto.
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Journal ArticleDOI
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide.
Sandra Isabel,Lucía Graña-Miraglia,Jahir M. Gutierrez,Cedoljub Bundalovic-Torma,Helen E. Groves,Marc R. Isabel,Ali Reza Eshaghi,Samir N. Patel,Jonathan B. Gubbay,Tomi Poutanen,David S. Guttman,Susan M. Poutanen,Susan M. Poutanen +12 more
TL;DR: A missense mutation, D614G, is identified in the spike protein of SARS-CoV-2, which has emerged as a predominant clade in Europe and is spreading worldwide and is most likely neutral to protein function as it relates to its interaction with the human ACE2 receptor.
Posted ContentDOI
Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide
Sandra Isabel,Lucía Graña-Miraglia,Jahir M. Gutierrez,Cedoljub Bundalovic-Torma,Helen E. Groves,Marc R. Isabel,Ali Reza Eshaghi,Samir N. Patel,Jonathan B. Gubbay,Tomi Poutanen,David S. Guttman,Susan M. Poutanen,Susan M. Poutanen +12 more
TL;DR: A missense mutation, D614G, is identified in the spike protein of SARS-CoV-2, which has emerged as a predominant clade in Europe and is spreading worldwide and is most likely neutral to protein function as it relates to its interaction with the human ACE2 receptor.
Journal ArticleDOI
Phylogenomics Reveals Clear Cases of Misclassification and Genus-Wide Phylogenetic Markers for Acinetobacter.
TL;DR: This study established the most up-to-date view of the evolutionary relationships within this genus and highlighted several cases of poor classification, especially for the very closely related species within the Acinetobacter calcoaceticus–Acinetobacteria baumannii complex (Acb complex).
Journal ArticleDOI
Rapid Gene Turnover as a Significant Source of Genetic Variation in a Recently Seeded Population of a Healthcare-Associated Pathogen.
Lucía Graña-Miraglia,Luis Lozano,Consuelo Velázquez,Patricia Volkow-Fernández,Ángeles Pérez-Oseguera,Miguel A. Cevallos,Santiago Castillo-Ramírez +6 more
TL;DR: Results show that rapid gene turnover has been of paramount importance in producing genetic variation within this population and demonstrate the utility of genome sequencing to study alternative forms of genetic variation.
Journal ArticleDOI
Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii.
TL;DR: The limitations of multilocus sequence typing are demonstrated using a robust genome phylogeny for typing Acinetobacter baumannii, showing it cannot reflect the true relationships of isolates for species with very dynamic genomes.