L
Lucian L. Leape
Researcher at Harvard University
Publications - 280
Citations - 41589
Lucian L. Leape is an academic researcher from Harvard University. The author has contributed to research in topics: Patient safety & Health care. The author has an hindex of 76, co-authored 280 publications receiving 40172 citations. Previous affiliations of Lucian L. Leape include University of Texas MD Anderson Cancer Center & University of Washington.
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Journal ArticleDOI
Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I.
Troyen A. Brennan,Lucian L. Leape,Nan M. Laird,Liesi E. Hebert,A R Localio,Ann G. Lawthers,Joseph P. Newhouse,Paul C. Weiler,Howard H. Hiatt +8 more
TL;DR: There is a substantial amount of injury to patients from medical management, and many injuries are the result of substandard care.
Journal ArticleDOI
The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II
Lucian L. Leape,Troyen A. Brennan,Nan M. Laird,Ann G. Lawthers,A R Localio,B A Barnes,Liesi E. Hebert,Joseph P. Newhouse,Paul C. Weiler,Howard H. Hiatt +9 more
TL;DR: The high proportion that are due to management errors suggests that many others are potentially preventable now, and reducing the incidence of these events will require identifying their causes and developing methods to prevent error or reduce its effects.
Journal ArticleDOI
Effect of computerized physician order entry and a team intervention on prevention of serious medication errors.
David W. Bates,Lucian L. Leape,David J. Cullen,Nan M. Laird,Laura A. Petersen,Jonathan M. Teich,Elizabeth Burdick,Mairead L. Hickey,Sharon Kleefield,Brian T. Shea,Martha Vander Vliet,Diane L. Seger +11 more
TL;DR: Physician computer order entry decreased the rate of nonintercepted serious medication errors by more than half, although this decrease was larger for potential ADEs than for errors that actually resulted in an ADE.
Journal ArticleDOI
Systems Analysis of Adverse Drug Events
Lucian L. Leape,David W. Bates,D J Cullen,Jeffrey B. Cooper,H J Demonaco,T Gallivan,Hallisey R,J Ives,Nan M. Laird,G Laffel +9 more
TL;DR: It is simply not scientifically possible to estimate current national iatrogenic injury and death rates based solely on the Harvard Medical Practice Study's (MPS) decade-old sample of patient discharge records, which included only one state during just 1 year (1984).
Journal ArticleDOI
The costs of adverse drug events in hospitalized patients
David W. Bates,Nathan Spell,David J. Cullen,Elisabeth Burdick,Nan M. Laird,Laura A. Petersen,Stephen D. Small,Bobbie Jean Sweitzer,Lucian L. Leape +8 more
TL;DR: The substantial costs of ADEs to hospitals justify investment in efforts to prevent these events, and estimates of annual costs attributable to all ADEs and preventable ADEs for a 700-bed teaching hospital are $5.6 million and $2.8 million are conservative because they do not include the costs of injuries to patients or malpractice costs.