Showing papers by "Luciano A. Sposato published in 2011"
TL;DR: A low frequency of NOAF was found after CEA and was associated with perioperative ischemic stroke and with the combined outcome of ischema stroke and myocardial infarction and was related to adverse postoperative outcome.
19 citations
TL;DR: Esta revision constituye una actualizacion y un extenso analisis oficial de la evidencia cientifica publicada publicada antes oficiembre of 2009.
14 citations
Journal Article•
TL;DR: Optizing the quality of medical treatment in recent decades has led to a significant reduction in stroke risk in patients not undergoing surgery, and medical therapy is the treatment of choice for patients with asymptomatic atherosclerotic disease of the extracranial carotid arteries.
Abstract: The reported prevalence of asymptomatic atherosclerotic disease of the extracranial internal carotid artery is up to 125% Carotid angioplasty has not yet proven safe and effective enough to prevent ischemic stroke in these patients Randomized studies showed that carotid endarterectomy is superior to medical therapy in reducing the risk of ischemic stroke when performed by surgical teams with complication rates (stroke or death) of less than 3% However, recruitment of these patients began more than 25 years ago, when the use of antiplatelet agents was lower than today, the treatment of hypertension was less effective than currently, and statins were not considered as key components of vascular prevention strategies Optimizing the quality of medical treatment in recent decades has led to a significant reduction in stroke risk in patients not undergoing surgery Based on these observations and with the exception of specific cases, medical therapy is the treatment of choice for patients with asymptomatic atherosclerotic disease of the extracranial carotid arteries
4 citations
TL;DR: Unemployment, 1 of these indicators, was associated with higher risk of stroke after adjusting for age and sex, and this association was significant for women, but not for men, in the main effect models.
Abstract: To the Editor:
We read with great interest the article, “Incidence of Stroke and Socioeconomic Neighborhood Characteristics. An Ecological Analysis of Dijon Stroke Registry” by Dr Grimaud et al.1 The authors found that low socioeconomic status was associated with higher incident risk of stroke in Dijon, France. The novel aspect was the use of a comprehensive set of 10 indicators for the assessment of socioeconomic status. Unemployment, 1 of these indicators, was associated with higher risk of stroke after adjusting for age and sex. This association was significant for women, but not for men, in the main effect models. However, a significant interaction was found between unemployment and age among men. Furthermore, unemployment was related …
4 citations
Journal Article•
TL;DR: This review examines the evidence on the prophylactic use of antiepileptic drugs in the neurological disorders above mentioned and investigates potential drug interactions, side effects, and neurotoxicity related to these drugs.
Abstract: Prophylactic use of antiepileptic drugs in neurological conditions such as ischemic and hemorrhagic stroke, subarachnoid hemorrhage, head injury, and brain tumors has been matter of debate for many years. These drugs are used for reducing secondary neurological damage caused by epileptic seizures. However, the evidence supporting this indication is scarce. Potential drug interactions, side effects, and even neurotoxicity related to these drugs have raised concern about this therapeutic approach. In this review, we examine the evidence on the prophylactic use of antiepileptic drugs in the neurological disorders above mentioned.