L
Luigi Pirtoli
Researcher at Temple University
Publications - 129
Citations - 2926
Luigi Pirtoli is an academic researcher from Temple University. The author has contributed to research in topics: Radiation therapy & Lung cancer. The author has an hindex of 24, co-authored 121 publications receiving 2448 citations. Previous affiliations of Luigi Pirtoli include Universidade Federal de Minas Gerais & University of Siena.
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Journal ArticleDOI
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours.
Clelia Miracco,Elena Cosci,Giuseppe Oliveri,Pietro Luzi,Lorenzo Pacenti,Irene Monciatti,Susanna Mannucci,Maria Caterina De Nisi,Marzia Toscano,Valeria Malagnino,Sara M. Falzarano,Luigi Pirtoli,Piero Tosi +12 more
TL;DR: In most high-grade astrocytic, ependymal neoplasms and atypical meningiomas the authors found a decrease of cytoplasmic protein expression that was, instead, high in the majority of low-grade tumours and in medulloblastomas, which further support its involvement also in brain tumours.
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Cetuximab and Radiotherapy Versus Cisplatin and Radiotherapy for Locally Advanced Head and Neck Cancer: A Randomized Phase II Trial
Stefano Maria Magrini,Michela Buglione,Renzo Corvò,Luigi Pirtoli,Fabiola Paiar,P. Ponticelli,Alessia Petrucci,Almalina Bacigalupo,Monica Crociani,Luciana Lastrucci,Stefania Vecchio,Pierluigi Bonomo,Nadia Pasinetti,Luca Triggiani,Roberta Cavagnini,L. Costa,S. Tonoli,Marta Maddalo,Salvatore Grisanti +18 more
TL;DR: CTX concomitant to RT lowered compliance and increased acute toxicity rates, and these results raise the issue of appropriately selecting patients with head and neck cancer who can benefit from CTX in combination with RT.
Journal ArticleDOI
microRNA-17 regulates the expression of ATG7 and modulates the autophagy process, improving the sensitivity to temozolomide and low-dose ionizing radiation treatments in human glioblastoma cells
Sergio Comincini,Giulia Allavena,Silvia Palumbo,Martina Morini,Francesca Durando,Francesca Angeletti,Luigi Pirtoli,Clelia Miracco +7 more
TL;DR: The study of the role of miR-17 in regulating ATG7 expression and autophagy reveals a novel function for this miRNA sequence in a critical cellular event with significant impacts in cancer development, progression and treatment.
Journal ArticleDOI
The prognostic role of Beclin 1 protein expression in high-grade gliomas.
Luigi Pirtoli,Gabriele Cevenini,Paolo Tini,Marta Vannini,Giuseppe Oliveri,Stefania Marsili,Vasileios Mourmouras,Giovanni Rubino,Clelia Miracco +8 more
TL;DR: High Grade Gliomas have a poor outcome, however, prognostic sub-groups of patients may be individuated by some clinico-biological parameters, and BPCE score might be added to pathological evaluation of HGG for prognostic purposes.
Journal ArticleDOI
Adjuvant Epirubicin With or Without Ifosfamide for Adult Soft-Tissue Sarcoma
Roberto Petrioli,Andrea Coratti,Pierpaolo Correale,Carlo D'Aniello,Luca Grimaldi,G. Tanzini,Serenella Civitelli,Stefania Marsili,Simona Messinese,G Marzocca,Luigi Pirtoli,Guido Francini +11 more
TL;DR: The results of the study suggest a possible advantage of epirubicin-based adjuvant chemotherapy in patients with soft-tissue sarcoma at high risk of relapse.