L
Luís Raposo
Researcher at Universidade Nova de Lisboa
Publications - 64
Citations - 1635
Luís Raposo is an academic researcher from Universidade Nova de Lisboa. The author has contributed to research in topics: Myocardial infarction & Internal medicine. The author has an hindex of 16, co-authored 51 publications receiving 1125 citations. Previous affiliations of Luís Raposo include University of Porto & Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa.
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Journal ArticleDOI
Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine's Tool Box.
Pedro Martins,João Jesus,Sofia Duque Santos,Luís Raposo,Catarina Roma-Rodrigues,Pedro V. Baptista,Alexandra R. Fernandes,Alexandra R. Fernandes +7 more
TL;DR: This review provides for a concise overview of heterocyclic active compounds and families and their main applications in medicine, focusing on those suitable for cancer therapy while simultaneously addressing main biochemical modes of action, biological targets, structure-activity relationships as well as intrinsic limitation issues in the use of these compounds.
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Genome-Wide Identification of Saccharomyces cerevisiae Genes Required for Maximal Tolerance to Ethanol
TL;DR: The increased expression of FPS1 confirmed the important role of this gene in alcoholic fermentation, leading to increased final ethanol concentration under conditions that lead to high ethanol production.
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Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis.
João Conde,Miguel Larguinho,Ana Cordeiro,Luís Raposo,Pedro M. Costa,Susana Santos,Mário Diniz,Alexandra R. Fernandes,Pedro V. Baptista +8 more
TL;DR: An integrated toxicology evaluation showed that the proposed nanotheranostics strategy does not exhibit significant toxicity, which is extremely relevant when translating into in vivo systems.
Journal ArticleDOI
Nanotheranostics Targeting the Tumor Microenvironment.
Catarina Roma-Rodrigues,Ines Pombo,Luís Raposo,Pedro Pedrosa,Alexandra R. Fernandes,Pedro V. Baptista +5 more
TL;DR: Recent developments relying on the properties of gold nanoparticles as the basis for nanotheranostics systems against the heterogeneity within the TME are focused on.
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Enhancement of water solubility of poorly water-soluble drugs by new biocompatible N-acetyl amino acid N-alkyl cholinium-based ionic liquids
Ana R. Jesus,Mário R. C. Soromenho,Luís Raposo,José M. S. S. Esperança,Pedro V. Baptista,Alexandra R. Fernandes,Patrícia M. Reis +6 more
TL;DR: A straightforward approach for the enhancement of the water solubility of paracetamol and sodium diclofenac is presented, using new biocompatible N‐acetyl amino acid N‐alkyl cholinium‐based ionic liquids as co‐solvents.