L
Luuk J. Rijzewijk
Researcher at VU University Medical Center
Publications - 33
Citations - 2641
Luuk J. Rijzewijk is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Type 2 diabetes & Pioglitazone. The author has an hindex of 19, co-authored 33 publications receiving 2372 citations. Previous affiliations of Luuk J. Rijzewijk include VU University Amsterdam.
Papers
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Journal ArticleDOI
Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus
Luuk J. Rijzewijk,Rutger W. van der Meer,Johannes W. A. Smit,Michaela Diamant,Jeroen J. Bax,Sebastiaan Hammer,Johannes A. Romijn,Albert de Roos,Hildo J. Lamb +8 more
TL;DR: Multivariable analysis indicated that myocardial triglyceride content was associated with E/A and E peak deceleration, independently of diabetic state, age, BMI, heart rate, visceral fat, and diastolic blood pressure.
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Altered Myocardial Substrate Metabolism and Decreased Diastolic Function in Nonischemic Human Diabetic Cardiomyopathy Studies With Cardiac Positron Emission Tomography and Magnetic Resonance Imaging
Luuk J. Rijzewijk,Rutger W. van der Meer,Hildo J. Lamb,Hugo W. A. M. de Jong,Mark Lubberink,Johannes A. Romijn,Jeroen J. Bax,Albert de Roos,Jos W. R. Twisk,Robert J. Heine,Adriaan A. Lammertsma,Johannes W. A. Smit,Michaela Diamant +12 more
TL;DR: Evaluating myocardial substrate and high-energy phosphate metabolism in asymptomatic men with well-controlled, uncomplicated type 2 diabetes with verified absence of cardiac ischemia and age-matched control subjects found no direct relation between cardiac diastolic function and parameters of myocardia metabolism.
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Findings from left ventricular strain and strain rate imaging in asymptomatic patients with type 2 diabetes mellitus.
Arnold C.T. Ng,Victoria Delgado,Matteo Bertini,Rutger W. van der Meer,Luuk J. Rijzewijk,Miriam Shanks,Gaetano Nucifora,Johannes W. A. Smit,Michaela Diamant,Johannes A. Romijn,Albert de Roos,Dominic Y. Leung,Hildo J. Lamb,Jeroen J. Bax +13 more
TL;DR: In this paper, a 2-dimensional speckle tracking was used to detect subtle myocardial dysfunction in 47 asymptomatic, male patients (age 57 ± 6 years) with type 2 diabetes mellitus.
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Pioglitazone Improves Cardiac Function and Alters Myocardial Substrate Metabolism Without Affecting Cardiac Triglyceride Accumulation and High-Energy Phosphate Metabolism in Patients With Well-Controlled Type 2 Diabetes Mellitus
Rutger W. van der Meer,Luuk J. Rijzewijk,Hugo W. A. M. de Jong,Hildo J. Lamb,Mark Lubberink,Johannes A. Romijn,Jeroen J. Bax,Albert de Roos,Otto Kamp,Walter Paulus,Robert J. Heine,Adriaan A. Lammertsma,Johannes W. A. Smit,Michaela Diamant +13 more
TL;DR: In T2DM patients, pioglitazone was associated with improvement in some measures of left ventricular diastolic function, myocardial glucose uptake, and whole-body insulin sensitivity, but the functional changes were not associated with myocardia substrate and high-energy phosphate metabolism.
Journal ArticleDOI
Myocardial Steatosis and Biventricular Strain and Strain Rate Imaging in Patients With Type 2 Diabetes Mellitus
Arnold C.T. Ng,Victoria Delgado,Matteo Bertini,Rutger W. van der Meer,Luuk J. Rijzewijk,See Hooi Ewe,Hans-Marc J. Siebelink,Johannes W. A. Smit,Michaela Diamant,Johannes A. Romijn,Albert de Roos,Dominic Y. Leung,Hildo J. Lamb,Jeroen J. Bax +13 more
TL;DR: High myocardial triglyceride content is associated with more pronounced impairment of LV and RV functions in men with uncomplicated type 2 diabetes mellitus.