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Lynda Mainville

Researcher at Montreal Neurological Institute and Hospital

Publications -  23
Citations -  3168

Lynda Mainville is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Cholinergic neuron & Cholinergic. The author has an hindex of 20, co-authored 23 publications receiving 3000 citations.

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GABAergic neurons in the rat pontomesencephalic tegmentum: Codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus

TL;DR: Through the reticular formation, ventral tegmentum, raphe nuclei, and dorsal tegineritum, GAD‐positive cells were codistributed with larger cells, which included neurons immunostained on adjacent sections for glutamate, tyrosine hydroxylase (TH), serotonin, or choline acetyltransferase (ChAT).
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GABAergic and other noncholinergic basal forebrain neurons, together with cholinergic neurons, project to the mesocortex and isocortex in the rat

TL;DR: This study investigated whether GABAergic neurons also contribute to the projection from the basal forebrain to neocortical regions, including the mesocortex (limbic) and the isocortex in the rat.
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Codistribution of GABA- with acetylcholine-synthesizing neurons in the basal forebrain of the rat.

TL;DR: The relationship of the GABA‐synthesizing neurons to the acetylcholine‐synsizing neurons was examined by application of a sequential double staining immunohistochemical procedure involving the peroxidase‐antiperoxidases technique for glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT).
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Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery.

TL;DR: Results indicate that GABAergic neurons are active during PS and could thus be responsible for inhibiting neighboring monoaminergic neurons that may be essential in the generation of PS.
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Discharge profiles across the sleep-waking cycle of identified cholinergic, GABAergic, and glutamatergic neurons in the pontomesencephalic tegmentum of the rat

TL;DR: Through different discharge profiles, the cholinergic, GABAergic, and glutamatergic neurons of the LDT, SubLDT, and MPPT thus appear to play distinct roles in promoting W and PS with cortical activation, PS with muscle atonia, or W with muscle tone.