M
M. Abul Kalam
Researcher at University of Connecticut
Publications - 2
Citations - 170
M. Abul Kalam is an academic researcher from University of Connecticut. The author has contributed to research in topics: AP site & DNA polymerase. The author has an hindex of 2, co-authored 2 publications receiving 159 citations.
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Journal ArticleDOI
Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells
M. Abul Kalam,Kazuhiro Haraguchi,Sushil Chandani,Edward L. Loechler,Maasaki Moriya,Marc M. Greenberg,Ashis K. Basu +6 more
TL;DR: This is the first investigation using extrachromosomal probes containing a Fapy·dG or Fap·dA site-specifically incorporated, which showed unequivocally that in simian kidney cells Fapy–G→T substitutions occur at a higher frequency than 8-oxo-G →T and that Fapy ·dA is very weakly mutagenic, as is 8-Oxo-dA.
Journal ArticleDOI
Mutagenesis of 8-oxoguanine adjacent to an abasic site in simian kidney cells: tandem mutations and enhancement of G-->T transversions.
M. Abul Kalam,Ashis K. Basu +1 more
TL;DR: It is concluded that base incorporation opposite an AP site is sequence-dependent and a higher mutational frequency at the TG(8-oxo)U sequence may arise from a change in DNA polymerase that is more error prone.