M
M. Gerlach
Researcher at Ruhr University Bochum
Publications - 4
Citations - 96
M. Gerlach is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Neuroprotection & Selegiline. The author has an hindex of 4, co-authored 4 publications receiving 95 citations.
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BookDOI
Parkinson’s Disease and Related Disorders
TL;DR: Die Online-Fachbuchhandlung beck-shop.de ist spezialisiert auf Fachbücher, insbesondere Recht, Steuern und Wirtschaft, und ergänzt das Programm durch Services wie Neuerscheinungsdienst oder Zusammenstellungen von Büchern zu Sonderpreisen.
Book ChapterDOI
New horizons in molecular mechanisms underlying Parkinson’s disease and in our understanding of the neuroprotective effects of selegiline
TL;DR: The concept that excitotoxicity is linked with the generation of free radicals is considered and how selegiline might exert its neuroprotective effects via indirect actions on the polyamine binding site of the NMDA receptor is discussed.
Book ChapterDOI
Is selegiline neuroprotective in Parkinson's disease?
TL;DR: Selegiline appears to exhibit other mechanisms of action which are independent of its action on MAO-B, including induction of superoxide dismutase, stimulation of neurotrophic factor synthesis, antagonistic modulation of the polyamine binding site of the NMDA-receptor
Book ChapterDOI
The Mode of Action of MAO-B Inhibitors
TL;DR: Monoamine oxidase (EC 1.3.4; amine: oxygen oxidoreductase (deaminating; flavin-containing) (MAO) is an enzyme of the outer mitochondrial membrane and catalyzes the oxidative deamination of amines according to the overall equation