M
M. Iris Hermanns
Researcher at University of Mainz
Publications - 20
Citations - 877
M. Iris Hermanns is an academic researcher from University of Mainz. The author has contributed to research in topics: Endothelial stem cell & Mean platelet volume. The author has an hindex of 11, co-authored 20 publications receiving 783 citations. Previous affiliations of M. Iris Hermanns include University of Applied Sciences, Mainz.
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Journal ArticleDOI
Expression of the endothelial markers PECAM-1, vWf, and CD34 in vivo and in vitro.
A. M. Müller,M. Iris Hermanns,Carmen Skrzynski,Maya Nesslinger,Klaus-Michael Müller,C. James Kirkpatrick +5 more
TL;DR: The results demonstrate the reduced expression of vessel type-specific endothelial phenotypes by endothelial monolayer cultures, stressing the need to improve culture conditions as well as develop cocultures and three-dimensional culture models.
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Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441.
Chiara Uboldi,Daniele Bonacchi,Giada Lorenzi,M. Iris Hermanns,Christine Pohl,Giovanni Baldi,Ronald E. Unger,C. James Kirkpatrick +7 more
TL;DR: The data suggest that the presence of contaminants, such as sodium citrate, on the surface of gold nanoparticles might play a pivotal role in inducing cytotoxicity in vitro, but does not influence the uptake of the particles in human ATII-like cell lines.
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Comparative study of adhesion molecule expression in cultured human macro- and microvascular endothelial cells.
TL;DR: The study suggests that E-selectin- and VCAM-coated beads could potentially serve in the isolation process of arteriolar and venular ECs, which are only partially transferable to in vivo conditions.
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Barrier functions and paracellular integrity in human cell culture models of the proximal respiratory unit
Christine Pohl,M. Iris Hermanns,Chiara Uboldi,Michaela Bock,Sabine Fuchs,Jasmin Dei-Anang,Eckhard Mayer,Kai Kehe,Wolfgang Kummer,Charles James Kirkpatrick +9 more
TL;DR: HBEC in coculture mimic the structure of native polarized bronchial epithelium showing basal, mucus-producing and ciliated cells, and provides an opportunity to examine the factors that influence barrier and mucociliary function of bronchia within a time frame of 3 weeks up to 3 months in an in vivo-like differentiated model.
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Hyperbranched PEG by random copolymerization of ethylene oxide and glycidol.
Daniel Wilms,Martina Schömer,Frederik R. Wurm,M. Iris Hermanns,C. James Kirkpatrick,Holger Frey +5 more
TL;DR: MTS assay demonstrated low cell toxicity of the hyperbranched PEG, comparable to the highly established linear PEG.