NMR Studies of Cyclodextrins and Cyclodextrin Complexes

The effect of the relative orientation and electronegativity of substituents on the magnitude of 3J(aa), 3J(ae) and 3J(ee) is well predicated by a simple set of additivity constants, valid for pyranose rings in carbohydrates. The proposed set of parameters is used to calculate 327 coupling constants [3J(HH)] in a variety of pyranosides and related compounds. A comparison with experimental values taken from the literature shows that couplings in molecules which are conformationally pure and underformed can be predicted with a surprising accuracy. An overall root-mean-square agreement of 0.29 Hz is attained for a selected group of 305 coupling values. A statistical breakdown of ΔJ(aa) and ΔJ(ae) [ΔJ=J(exp)-J(calc)] along each carbon-carbon bond in the pyranose systems reveals an unexpected degree of geometrical homogeneity.

Prediction of anti and gauche vicinal proton‐proton coupling constants in carbohydrates: A simple additivity rule for pyranose rings

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bip.1979.360180925

Conformations of the hydroxymethyl group in crystalline aldohexopyranoses

Organometallic Compounds and Living Organisms

Characterization of neutral sugars and uronic acids after methanolysis and trimethylsilylation for recognition of plant gums

https://dspace.library.uu.nl/bitstream/handle/1874/5280/17273.pdf;sequence=2

Conformational studies on pertrimethylsilyl derivatives of some mono- and disaccharides by 220 MHz PMR spectroscopy

https://dspace.library.uu.nl/bitstream/handle/1874/5175/17260.pdf;sequence=2

M.J.A. de Bie

Papers

Conformational studies on pertrimethylsilyl derivatives of some mono- and disaccharides by 220 MHz PMR spectroscopy

A PMR study of the anomeric protons in pertrimethylsilyl oligosaccharides, a determination of the configuration of the glycosidic bond