The addition of tomosynthesis to digital mammography offers the dual benefit of improved diagnostic accuracy and significant reduction in false-positive recall rate, thereby avoiding unnecessary additional testing and decreasing attendant anxiety, inconvenience, and cost for women.

/pdf/assessing-radiologist-performance-using-combined-digital-3gtokue65i.pdf

Assessing Radiologist Performance Using Combined Digital Mammography and Breast Tomosynthesis Compared with Digital Mammography Alone: Results of a Multicenter, Multireader Trial

The two-view combination of a synthesized two-dimensional view plus digital breast tomosynthesis should be considered acceptable for routine use in mammographic screening.

Two-View Digital Breast Tomosynthesis Screening with Synthetically Reconstructed Projection Images: Comparison with Digital Breast Tomosynthesis with Full-Field Digital Mammographic Images

Many important post-acquisition aspects of breast tomosynthesis imaging can impact its clinical performance. Chief among them is the reconstruction algorithm that generates the representation of the three-dimensional breast volume from the acquired projections. But even after reconstruction, additional processes, such as artifact reduction algorithms, computer aided detection and diagnosis, among others, can also impact the performance of breast tomosynthesis in the clinical realm. In this two part paper, a review of breast tomosynthesis research is performed, with an emphasis on its medical physics aspects. In the companion paper, the first part of this review, the research performed relevant to the image acquisition process is examined. This second part will review the research on the post-acquisition aspects, including reconstruction, image processing, and analysis, as well as the advanced applications being investigated for breast tomosynthesis.

/pdf/a-review-of-breast-tomosynthesis-part-ii-image-2wlpx9aiz2.pdf

A review of breast tomosynthesis. Part II. Image reconstruction, processing and analysis, and advanced applications

Breast tomosynthesis: state-of-the-art and review of the literature.

If digital breast tomosynthesis (DBT) is performed on the basis of an abnormal screening mammogram, then the sensitivity of DBT cannot exceed that of mammography.

/pdf/digital-breast-tomosynthesis-state-of-the-art-1hyi0i35g2.pdf

Digital Breast Tomosynthesis: State of the Art.

OBJECTIVE. The purpose of this article is to compare the ability of digital breast tomosynthesis and full field digital mammography (FFDM) to detect and characterize calcifications.MATERIALS AND METHODS. One hundred paired examinations were performed utilizing FFDM and digital breast tomosynthesis. Twenty biopsy-proven cancers, 40 biopsy-proven benign calcifications, and 40 randomly selected negative screening studies were retrospectively reviewed by five radiologists in a crossed multireader multimodal observer performance study. Data collected included the presence of calcifications and forced BI-RADS scores. Receiver operator curve analysis using BI-RADS was performed.RESULTS. Overall calcification detection sensitivity was higher for FFDM (0.84% [95% CI, 0.79–0.88%]) than for digital breast tomosynthesis (0.75% [95% CI, 0.70–0.80%]). In the cancer cohort, 75 (76%) of 99 interpretations identified calcification in both modes. Of those, a BI-RADS score less than or equal to 2 was rendered in three (4%) ...

https://www.ajronline.org/doi/pdfplus/10.2214/AJR.10.4656

Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: a comparison.

We present a case of bifid median nerve and a persistent median artery presenting in the setting of carpal tunnel syndrome. The importance of these anatomic variants and their imaging features and workup are discussed.

M. Lee Spangler

Papers

Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: a comparison.

A persistent median artery and bifid median nerve in the setting of carpal tunnel syndrome