Madhusmita Rout

TL;DR: Docking studies of 10 medicinal plant compounds and three drugs available in the market (control) with NS2 protease were employed by using rigid docking approach of AutoDock 4.2, showing that these compounds are potential inhibitors of the target and all these docked compounds have good inhibition constant.

TL;DR: An immunoinformatics pipeline is utilized for epitope-based peptide vaccine design, which can trigger a critical immune response against M. pneumoniae and its associated diseases, and predicts three peptides with good binding affinity towards HLA molecules as best T-cell and B-cell epitopes.

TL;DR: The study reveals that GDM has associations with diseases like type I and II diabetes mellitus, obesity, and preeclampsia, and could trace out a significant connection between the key molecules like LEP and placental growth hormone from mother and Placenta, which plays a critical role in INS secretion, INS signaling, and β‐cell dysfunction pathways.

TL;DR: In this paper , a template-based homology approach was used to model the three-dimensional (3D) structure of DdRp and virtual screening was performed to probe the molecular interactions between 1755 Food and Drug Administration-approved small molecule drugs (≤500 molecular weight) and the DNAdependent RNA polymerase of poxviruses.

TL;DR: In this paper , the impact of ApoC-III concentration on TG and lipoproteins and investigate the role of known rare loss-of-function APOC3 variants for modulating ApOc-III, TG concentrations and CVD risk in different ethnic groups.