WRITING GROUP MEMBERS Emelia J. Benjamin, MD, SCM, FAHA Michael J. Blaha, MD, MPH Stephanie E. Chiuve, ScD Mary Cushman, MD, MSc, FAHA Sandeep R. Das, MD, MPH, FAHA Rajat Deo, MD, MTR Sarah D. de Ferranti, MD, MPH James Floyd, MD, MS Myriam Fornage, PhD, FAHA Cathleen Gillespie, MS Carmen R. Isasi, MD, PhD, FAHA Monik C. Jiménez, ScD, SM Lori Chaffin Jordan, MD, PhD Suzanne E. Judd, PhD Daniel Lackland, DrPH, FAHA Judith H. Lichtman, PhD, MPH, FAHA Lynda Lisabeth, PhD, MPH, FAHA Simin Liu, MD, ScD, FAHA Chris T. Longenecker, MD Rachel H. Mackey, PhD, MPH, FAHA Kunihiro Matsushita, MD, PhD, FAHA Dariush Mozaffarian, MD, DrPH, FAHA Michael E. Mussolino, PhD, FAHA Khurram Nasir, MD, MPH, FAHA Robert W. Neumar, MD, PhD, FAHA Latha Palaniappan, MD, MS, FAHA Dilip K. Pandey, MBBS, MS, PhD, FAHA Ravi R. Thiagarajan, MD, MPH Mathew J. Reeves, PhD Matthew Ritchey, PT, DPT, OCS, MPH Carlos J. Rodriguez, MD, MPH, FAHA Gregory A. Roth, MD, MPH Wayne D. Rosamond, PhD, FAHA Comilla Sasson, MD, PhD, FAHA Amytis Towfighi, MD Connie W. Tsao, MD, MPH Melanie B. Turner, MPH Salim S. Virani, MD, PhD, FAHA Jenifer H. Voeks, PhD Joshua Z. Willey, MD, MS John T. Wilkins, MD Jason HY. Wu, MSc, PhD, FAHA Heather M. Alger, PhD Sally S. Wong, PhD, RD, CDN, FAHA Paul Muntner, PhD, MHSc On behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart Disease and Stroke Statistics—2017 Update

Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

Harrison's Principles of Internal Medicine

March 5, 2019 e1 WRITING GROUP MEMBERS Emelia J. Benjamin, MD, ScM, FAHA, Chair Paul Muntner, PhD, MHS, FAHA, Vice Chair Alvaro Alonso, MD, PhD, FAHA Marcio S. Bittencourt, MD, PhD, MPH Clifton W. Callaway, MD, FAHA April P. Carson, PhD, MSPH, FAHA Alanna M. Chamberlain, PhD Alexander R. Chang, MD, MS Susan Cheng, MD, MMSc, MPH, FAHA Sandeep R. Das, MD, MPH, MBA, FAHA Francesca N. Delling, MD, MPH Luc Djousse, MD, ScD, MPH Mitchell S.V. Elkind, MD, MS, FAHA Jane F. Ferguson, PhD, FAHA Myriam Fornage, PhD, FAHA Lori Chaffin Jordan, MD, PhD, FAHA Sadiya S. Khan, MD, MSc Brett M. Kissela, MD, MS Kristen L. Knutson, PhD Tak W. Kwan, MD, FAHA Daniel T. Lackland, DrPH, FAHA Tené T. Lewis, PhD Judith H. Lichtman, PhD, MPH, FAHA Chris T. Longenecker, MD Matthew Shane Loop, PhD Pamela L. Lutsey, PhD, MPH, FAHA Seth S. Martin, MD, MHS, FAHA Kunihiro Matsushita, MD, PhD, FAHA Andrew E. Moran, MD, MPH, FAHA Michael E. Mussolino, PhD, FAHA Martin O’Flaherty, MD, MSc, PhD Ambarish Pandey, MD, MSCS Amanda M. Perak, MD, MS Wayne D. Rosamond, PhD, MS, FAHA Gregory A. Roth, MD, MPH, FAHA Uchechukwu K.A. Sampson, MD, MBA, MPH, FAHA Gary M. Satou, MD, FAHA Emily B. Schroeder, MD, PhD, FAHA Svati H. Shah, MD, MHS, FAHA Nicole L. Spartano, PhD Andrew Stokes, PhD David L. Tirschwell, MD, MS, MSc, FAHA Connie W. Tsao, MD, MPH, Vice Chair Elect Mintu P. Turakhia, MD, MAS, FAHA Lisa B. VanWagner, MD, MSc, FAST John T. Wilkins, MD, MS, FAHA Sally S. Wong, PhD, RD, CDN, FAHA Salim S. Virani, MD, PhD, FAHA, Chair Elect On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

http://diposit.ub.edu/dspace/bitstream/2445/122776/1/gbd2016riskfactorscollaborators2017_3028.pdf

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Selenium (Se) is an essential mineral element needed by livestock and human. The amount of Se intake is largely determined by the Se content in the plants (food and feed) consumed. This study aimed to analyze the effect of Se fertilizer on the morphological characters, biomass yield, nutrient content, and in vitro nutrient digestibility of Cichorium intybus . This study was conducted for four months, starting from May to August 2019, located at the Faculty of Animal Science, Universitas Gadjah Mada. The seeds of Cichorium intybus var. Chico was sown in 24 plots and the plots were arranged in a completely randomized block design. Three levels of Se fertilization treatments (0, 3.5, and 7.5 mg/m2) were applied with 8 replicates. Plant defoliation on every 45 days: namely the first defoliation (from sowing to 45 days), the second defoliation (regrowth 1 up to 45 days), and the third defoliation (regrowth 2 up to 45 days). In all studied parameters, the results showed that chicory with Se fertilizer (3.5 and 7.5 mg/m2) was higher (p<0.05) than chicory without Se fertilization. The chicory with Se fertilizer at the level of 7.5 mg/m2 had higher (p<0.05) leaf width, biomass yield, crude protein, and Se content, and in vitro nutrient digestibility (dry matter, organic matter, crude protein) compared to that with Se fertilizer at the level of 3.5 mg/m2. Chicory at the third defoliation had a higher biomass yield and Se content than at the second defoliation. In conclusion, the best combination from this study was the third defoliation, with Se fertilizer level of 7.5 mg/m2. 

Selenium Application in Improving Chicory (Cichorium intybus) Productivity and Quality

Deep Learning algorithms are often used as black box type learning and they are too complex to understand. The widespread usability of Deep Learning algorithms to solve various machine learning problems demands deep and transparent understanding of the internal representation as well as decision making. Moreover, the learning models, trained on sequential data, such as audio and video data, have intricate internal reasoning process due to their complex distribution of features. Thus, a visual simulator might be helpful to trace the internal decision making mechanisms in response to adversarial input data, and it would help to debug and design appropriate deep learning models. However, interpreting the internal reasoning of deep learning model is not well studied in the literature. In this work, we have developed a visual interactive web application, namely d-DeVIS, which helps to visualize the internal reasoning of the learning model which is trained on the audio data. The proposed system allows to perceive the behavior as well as to debug the model by interactively generating adversarial audio data point. The web application of d-DeVIS is available at ddevis.herokuapp.com.

A Gray Box Interpretable Visual Debugging Approach for Deep Sequence Learning Model

Quail Rearing Practices and Potential for Avian Influenza Virus Transmission, Bangladesh.

Introduction: Cervical spine injuries represent 2 to 6% of adult blunt trauma, and one third of all spinal injuries. Anterior approach of operative management of cervical spinal injury with incomplete neurological lesion has least analyzed in our settings, the present study has been designed to evaluate the outcome of ACDF and stabilization by cervical plate and screw for managing traumatic cervical spine injury with incomplete neurological deficit.Methods: This study was conducted at NITOR, Dhaka, from July 2016 to June 2018.Twenty available patients meeting the inclusion & exclusion criteria were included. All cases were properly evaluated pre-operatively and underwent ACDF & stabilization with cervical plate and screws. Follow up was done for 5 to 12 months. The final assessment was done by ASIA impairment scale, MRC grading, Bridewell fusion grade, Denis work & pain scale and modified Odom’s criteria.Results: Highest number of patients 10 (50%) were in ASIA grade B, 7(35.0%) patients were in ASIA grade D and 3(15.0%) patients were in ASIA grade C on admission. But in last follow up, highest number of patients were in ASIA grade E (45%). The ASIA grade has improved 1 grade in 55% cases. Bridewell fusion grade showed anterior fusion grade I in 55% of cases, grade II in 45% cases. 60% of cases were in W2 group of Denis work scale after last follow up. Early post-operative complications were dysphagia (20%), respiratory distress (5%) and neck pain (20%). Late post-operative complications were neck pain (10%), donor site pain (5%) and bed sore (5%). According to modified Odom’s criteria, 65% of the cases were found excellent.Conclusion: On the basis of the results in this study, it can be said that anterior cervical decompression, stabilization and fusion by bone graft of the patients who have traumatic unstable cervical spine injury with incomplete neurological lesion will provide effective benefit. 

Anterior Cervical Discectomy and Fusion (ACDF) with Stabilization by cervical locking plate and screw in traumatic sub-axial incomplete cervical spine injury: Early experience

Background: The concept of eco-toilets in Bangladesh was promoted by an NGO (Practical Action, Bangladesh). The ecotoilets are especially built to collect human excreta for using them as manure on the fields after appropriate treatment for 12 months.
Objectives: This study was designed to see the physical properties appropriate for fields and pathogenic potential to ensure the treated human excreta are safe for cultivator’s handling.
Methodology: The study was carried out in three phases during 2010 to 2014. A total of 210 composted faecal excreta were examined for physical properties like colour, odour, odour intensity, moisture, bacteriological examination for faecally transmitted potential bacteria and parasitological examination for ova / cysts of faecally - transmitted parasites to recommend whether these composted excreta were suitable for use as manure by the cultivators.
Results: Majority of the specimens in all three phases contained remarkable moisture: 22.3-80.0% in all specimens in phase I, a considerable number (16, 53.3%) contained 25% moisture in phase II and high moisture content (66.4%-78.9%) in 6(50.0%) of specimens in phase III. Bacteriological examination revealed no pathogenic organism in any specimen of the phases- although, some specimens in all phases showed growth of non-coliform bacteria. Parasitological examinations in all phases revealed ova/larvae of helminths of Ascaris lumbricoides (AL)/ Trichuris trichiura (TT)/ Strongyloides stercoralis (SS). No cyst or trophozoite of any pathogenic parasite, or oocyst of the cryptosporidium was found.
Conclusion: The composted excreta could not be adequately treated by sun-drying as indicated by high moisture content and were found not suitable to use as manure by cultivators in the field.
J Monno Med Coll June 2022;8(2): 44-47

/pdf/pathogenic-potential-of-composted-and-sundried-human-excreta-3s378t9t.pdf

Mahmudur Rahman

Papers

Selenium Application in Improving Chicory (Cichorium intybus) Productivity and Quality

A Gray Box Interpretable Visual Debugging Approach for Deep Sequence Learning Model

Quail Rearing Practices and Potential for Avian Influenza Virus Transmission, Bangladesh.

Anterior Cervical Discectomy and Fusion (ACDF) with Stabilization by cervical locking plate and screw in traumatic sub-axial incomplete cervical spine injury: Early experience

Pathogenic Potential of Composted and Sundried Human Excreta from Eco-toilets in Bangladesh