https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1096-0031.2008.00212.x

Plant Systematics: A Phylogenetic Approach

Medicinal plants are important sources for discovering new drugs for many diseases and disorders. From times immemorial, plants are being used to cure many ailments and recently the trend of use of this green medicine has increased. This is merely because medicinal plants are free from many side effects that are generally associated with synthetic drugs, they are easily available and affordable by all the people. The diversity of medicinal plants is vast and there is cure for any and every ailment in them. They may be directly used as drugs or they may act as lead molecules for the discovery of new drug candidates. Many of the drugs used for deadly diseases like cancer are of plant origin (Chanda and Nagani, 2013). International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 9 Number 8 (2020) Journal homepage: http://www.ijcmas.com

Best from Waste: Therapeutic Potential of Plant Waste (Seeds, Peels, Flowers)

Impact of citronellol on river and soil environments using non-target model organisms and natural populations.

Modern medicine is struggling with the problem of fully effective treatment of neoplastic diseases despite deploying innovative chemotherapeutic agents. Therefore, undertaking cancer-prevention measures, such as proper eating habits, should be strongly recommended. The present research aimed to compare the effects of juice from young shoots of beetroot compared to juice from root at full maturity on human breast cancer and normal cells. The juice from young shoots, both in the native and digested form, was most often a significantly stronger inhibitor of the proliferation of both analyzed breast cancer cell lines (MCF-7 and MDA-MB-231), compared to the native and digested juice from red beetroot. Regardless of juice type, a significantly greater reduction was most often shown in the proliferation of estrogen-dependent cells (MCF-7 line) than of estrogen-independent cells (MDA-MB-231 line). All analyzed types of beetroot juice and, in particular, the ones from young shoots and the root subjected to digestion and absorption, exerted an antiproliferative and apoptotic effect (pinpointing the internal apoptosis pathway) on the cells of both cancer lines studied. There is a need to continue the research to comprehensively investigate the factors responsible for both these effects.

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Young Shoots of Red Beet and the Root at Full Maturity Inhibit Proliferation and Induce Apoptosis in Breast Cancer Cell Lines

Plants have been used for many years as a source of traditional medicine to treat various diseases and conditions. Beta Vulgaris Linnaeus ranks among the 10 most powerful vegetables as excellent sources for phytochemicals, which showed potent antioxidant and anticancer activities. The aim of this study is to characterize the chemical composition and determine the cytotoxicity and antibacterial activity of B.Vulgaris roots extract. The results of GC-Ms analysis of the unsaponifiable matter of B.Vulgaris roots showed the presence of 18 components. The undecane is the major hydrocarbon compound and α-citronellol is the major oxygenated compound. The methanolic extract of B.Vulgaris roots were enriched with a complicated mixture of phenolic acids and flavoniod which elucidated for the first time from this plant , including polyphenolic acid; ellagic acid (1); pyrogallol(2); salicylic(3); catechol(4); benzoic(5); protocatchuic (6); chlorogenic(7); p-hydroxy benzoic acids (8) . The molecular components of a flavoniod fraction, obtained from liquid chromatography extract, were identified using HPLC -ESI -MS. The major components were vitexin -2" -O-rhamnoside (1); demethylated -2"-xylosylvitexin (2); isorhamnetin -3-gentiobioside (3); rutin(4); beside minor components , luteolin-6-arabinose-8-glucose(1); hesperidin (2); acacetin (3); kaempferol-3-(2 -p -comaroyl) glucose (4); apigenin 6 -arabinose -8-glactose (5); quercetin (6); naringin (7). The structures of all isolated compounds were elucidated by conventional methods, spectroscopic analysis alongside their mass spectrometric investigations. The search for new, potentially biologically active extract becomes much more efficient after identification of all compounds in that mixture. The cytotoxic activity of methanolic extract was evaluated against pancreatic carcinoma (PANC-1) , hepatocellular carcinoma cell line HEPG-2 and , Lung carcinoma (A549) using MTT assay and vinblastine as a reference drug. methanolic extract showed higher activity with (IC50=3.69 µg/ml), mild cytotoxic activity against HepG2 with (IC50=4.43 µg/ml) ,Lung carcinoma (A549) with (IC50=4.9 µg/ml) and a weak activity against prostate carcinoma PC-3 with (IC50=6.1 µg/ml). The antimicrobial activity of B.Vulgaris roots methanolic extract was evaluated using agar well diffusion method towards two representatives for each of Gram positive and Gram negative bacteria. The extract demonstrated inhibitory effect against pathogenic microorganisms: Staphylococcus aureus, ATCC 29213; (ZI=24mm) strains and Pseudomonas aerogenasa ATCC 27853); (ZI=19.3 mm) at 100 µL concentration.

https://ejchem.journals.ekb.eg/article_53694_eca548d94df60d92cc33b860198f19a2.pdf

Mahrous G.M. Mahdi

Papers

Chemical Composition and Biological Activities of Red beetroot (Beta Vulgaris Linnaeus) Roots