https://pubs.rsc.org/en/content/articlepdf/2019/NP/C8NP00092A

Marine natural products.

https://chemistry.mdma.ch/hiveboard/rhodium/pdf/nef.reaction.review.2004.pdf

Recent synthetic developments in the nitro to carbonyl conversion (Nef reaction)

Intramolecular 1,3-dipolar cycloaddition reactions in targeted syntheses

A synthon approach to spiro compounds

The structures of natural products from a variety of sources contain spirocycles, two rings that share a common atom. The spiro motif is finding increasing inclusion in drug candidates, and as a structural component in several promising classes of chiral ligands used in asymmetric synthesis. Total syntheses of products containing all-carbon spirocycles feature several common methods of ring closure which we examine in this review.

/pdf/total-syntheses-of-natural-products-containing-57gpx24kea.pdf

Total syntheses of natural products containing spirocarbocycles

An efficient synthesis of spirobicyclic sesquiterpenes, (±)-spirojatamol 1 and (±)-erythrodiene 2, using an intramolecular 1,3-dipolar cycloaddition as the pivotal step is described.

A simple total synthesis of (±)-spirojatamol and (±)-erythrodiene via intramolecular 1,3-dipolar cycloaddition

An intramolecular aldol reaction of keto acetals 1, regioselectively
performed with Me3SiI–(Me3Si)2NH
leading to spirobicyclic compounds 2 and 3, has been applied to the
syntheses of (±)-spirojatamol and
(±)-erythrodiene.

Facile construction of spirobicyclic skeletons by intramolecular aldol reaction: simple formal syntheses of (±)-spirojatamol and (±)-erythrodiene

Facile Construction of Spirobicyclic Skeletons by Intramolecular Aldol Reaction: Simple Formal Syntheses of (.+‐.)‐Spirojatamol and (.+‐.)‐ Erythrodiene.

Maki Yagihashi

Papers

A simple total synthesis of (±)-spirojatamol and (±)-erythrodiene via intramolecular 1,3-dipolar cycloaddition

Facile construction of spirobicyclic skeletons by intramolecular aldol reaction: simple formal syntheses of (±)-spirojatamol and (±)-erythrodiene

Facile Construction of Spirobicyclic Skeletons by Intramolecular Aldol Reaction: Simple Formal Syntheses of (.+‐.)‐Spirojatamol and (.+‐.)‐ Erythrodiene.

Simple Total Synthesis of (.+‐.)‐Spirojatamol and (.+‐.)‐Erythrodiene via Intramolecular 1,3‐Dipolar Cycloaddition.