M
Malgorzata Kotulska
Researcher at Wrocław University of Technology
Publications - 80
Citations - 1007
Malgorzata Kotulska is an academic researcher from Wrocław University of Technology. The author has contributed to research in topics: Electroporation & Photodynamic therapy. The author has an hindex of 19, co-authored 75 publications receiving 811 citations.
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FISH Amyloid – a new method for finding amyloidogenic segments in proteins based on site specific co-occurence of aminoacids
Pawel Gasior,Malgorzata Kotulska +1 more
TL;DR: An original machine learning method for classification of aminoacid sequences, based on discovering a segment with a discriminative pattern of site-specific co-occurrences between sequence elements, which reveals characteristic classification pattern of the data and finds the segments where its scoring is the strongest, also in long training sequences.
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Electroporation and lipid nanoparticles with cyanine IR-780 and flavonoids as efficient vectors to enhanced drug delivery in colon cancer.
Julita Kulbacka,Agata Pucek,Malgorzata Kotulska,Magda Dubińska-Magiera,Joanna Rossowska,Marie-Pierre Rols,Kazimiera A. Wilk +6 more
TL;DR: The efficacy of nanoparticles with mixed cargo, additionally enhanced by electroporation, is demonstrated to act as an anticancer modality to eliminate cancer cells.
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Electroporation-induced changes in normal immature rat myoblasts (H9C2)
Iwona Kamińska,Malgorzata Kotulska,Anna Stecka,Jolanta Saczko,Malgorzata Drag-Zalesinska,Teresa Wysocka,Anna Choromanska,Nina Skolucka,Rafał Nowicki,Jakub Marczak,Julita Kulbacka +10 more
TL;DR: Experimental data on effects of electroporation in culture of cardiac cells (H9C2) is presented and MTT viability test showed that pulse intensities above 375 V/cm are destructive for myocytes viability.
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AmyLoad: website dedicated to amyloidogenic protein fragments
TL;DR: The AmyLoad website, which collects the amyloidogenic sequences from all major sources, allows for filtration of the fragments and provides detailed information about each of them, and can be used as a sequence analysis tool.
Journal ArticleDOI
Amyloidogenic motifs revealed by n-gram analysis.
Michał Burdukiewicz,Piotr Sobczyk,Stefan Rödiger,Anna Duda-Madej,Paweł Mackiewicz,Malgorzata Kotulska +5 more
TL;DR: The results showed sequential patterns in the amyloids which are strongly correlated with hydrophobicity, a tendency to form β-sheets, and lower flexibility of amino acid residues.