M
Man-Seok Park
Researcher at Chonnam National University
Publications - 168
Citations - 2745
Man-Seok Park is an academic researcher from Chonnam National University. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 27, co-authored 146 publications receiving 2123 citations.
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Proximal arterial occlusion in acute ischemic stroke with low NIHSS scores should not be considered as mild stroke.
TL;DR: This study demonstrates that symptomatic arterial occlusion may be an important predictor of END in patients with acute mild stroke, and it may therefore be important to consider that acute ischemic stroke with symptomatic arteries occlusions and low NIHSS scores may not represent mild stroke in acute periods.
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Effects of Flavonoid Compounds on β-amyloid-peptide-induced Neuronal Death in Cultured Mouse Cortical Neurons.
Seong-Min Choi,Byeong C. Kim,Yeun-Hee Cho,Kang-Ho Choi,Jane Chang,Man-Seok Park,Myeong-Kyu Kim,Ki-Hyun Cho,Jong-Keun Kim +8 more
TL;DR: Results demonstrated that oxidative stress was involved in Aβ-induced neuronal death, and antioxidative flavonoid compounds, especially epicatechin, EGCG, luteolin, and myricetin, could inhibit neuronal death.
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Acute Basilar Artery Occlusion: Differences in Characteristics and Outcomes after Endovascular Therapy between Patients with and without Underlying Severe Atherosclerotic Stenosis.
TL;DR: The occlusion segment of the basilar artery and the presence or absence of bilateral thalamic infarction on a pretreatment DWI might be helpful for predicting underlying intracranial atherosclerotic stenosis in patients with acute Basilar artery occlusions.
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Associations of BDNF Genotype and Promoter Methylation with Acute and Long-Term Stroke Outcomes in an East Asian Cohort
Jae-Min Kim,Robert Stewart,Man-Seok Park,Hee-Ju Kang,Sung-Wan Kim,Il-Seon Shin,Hye-Ran Kim,Myung-Geun Shin,Ki-Hyun Cho,Jin-Sang Yoon +9 more
TL;DR: A role for BDNF in poststroke recovery was supported, and clinical utility of BDNF genetic and epigenetic profile as prognostic biomarkers and a target for drug development was suggested.
Journal ArticleDOI
A Longitudinal Study of BDNF Promoter Methylation and Genotype With Poststroke Depression
Jae-Min Kim,Robert Stewart,Hee-Ju Kang,Seon-Young Kim,Sung-Wan Kim,Il-Seon Shin,Man-Seok Park,Hye-Ran Kim,Myung-Geun Shin,Ki-Hyun Cho,Jin-Sang Yoon +10 more
TL;DR: A role for BDNF in PSD was supported, and associations with BDNF gene methylation status may represent a target for drug development.