M
Manuela de Lima Toccafondo Vieira
Researcher at Center for Drug Evaluation and Research
Publications - 2
Citations - 151
Manuela de Lima Toccafondo Vieira is an academic researcher from Center for Drug Evaluation and Research. The author has contributed to research in topics: Health care & Physiologically based pharmacokinetic modelling. The author has an hindex of 2, co-authored 2 publications receiving 138 citations. Previous affiliations of Manuela de Lima Toccafondo Vieira include Universidade Federal de Minas Gerais.
Papers
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Journal ArticleDOI
Botanical-Drug Interactions: A Scientific Perspective
TL;DR: The potential pharmacokinetic and pharmacodynamic bases of such interactions are discussed, as well as the challenges associated with the interpretation of the available data and prediction of botanical-drug interactions.
Journal ArticleDOI
Towards Quantitation of the Effects of Renal Impairment and Probenecid Inhibition on Kidney Uptake and Efflux Transporters, Using Physiologically Based Pharmacokinetic Modelling and Simulations
Vicky Hsu,Manuela de Lima Toccafondo Vieira,Manuela de Lima Toccafondo Vieira,Ping Zhao,Lei Zhang,Jenny Huimin Zheng,Anna Nordmark,Eva Gil Berglund,Kathleen M. Giacomini,Shiew-Mei Huang +9 more
TL;DR: In this article, the effects of patient factors on kidney transporters were evaluated using physiologically based pharmacokinetic (PBPK) modeling to evaluate the effect of different patient factors.