scispace - formally typeset
M

Marc Descamps

Researcher at university of lille

Publications -  189
Citations -  6384

Marc Descamps is an academic researcher from university of lille. The author has contributed to research in topics: Glass transition & Differential scanning calorimetry. The author has an hindex of 45, co-authored 188 publications receiving 5896 citations. Previous affiliations of Marc Descamps include Centre national de la recherche scientifique & Lille University of Science and Technology.

Papers
More filters
Journal ArticleDOI

Solid state amorphization of pharmaceuticals.

TL;DR: The purpose of this short review paper is to illustrate the possibility to amorphize one compound by several different routes and to rationalize the observed transformations using the concepts of effective temperature introduced in nonequilibrium physics.
Journal ArticleDOI

Transformation of Pharmaceutical Compounds upon Milling and Comilling: The Role of Tg

TL;DR: It is shown that decreasing the milling temperature leads to an increase of the amorphization tendency whereas milling above T(g) can produce a crystal-to-crystal transformation between polymorphic varieties, contradict the usual suggestion that milling transforms the physical state only by a heating effect which induces a local melting.
Journal ArticleDOI

How homogeneous are the trehalose, maltose, and sucrose water solutions? An insight from molecular dynamics simulations.

TL;DR: The structural properties resulting from the reciprocal influence between water and three well-known homologous disaccharides in aqueous solutions have been investigated by means of molecular dynamics computer simulations and suggest that trehalose-water mixtures would be more homogeneous than the two others, thus reducing both desiccation stresses and ice formation.
Posted Content

How homogeneous are the trehalose, maltose and sucrose water solutions ? An Insight from Molecular Dynamics simulations

TL;DR: The structural properties of trehalose, maltose and sucrose in aqueous solutions have been investigated in the 4-66 wt % concentration range by means of molecular dynamics computer simulations as mentioned in this paper.
Journal ArticleDOI

Does the Interaction Potential Determine Both the Fragility of a Liquid and the Vibrational Properties of Its Glassy State

TL;DR: By performing molecular dynamics simulations of binary Lennard-Jones systems with three different potentials, it is shown that the increase of anharmonicity and capacity for intermolecular coupling of the potential is the cause of the increase in kinetic fragility and nonexponentiality in the liquid state and the T(g)-scaled temperature dependence of the nonergodicity parameter determined by the vibrations at low temperatures in the glassy state.